加拿大安大略省 50 岁及以上成年人中，mRNA COVID-19 单价和双价疫苗加强针针对奥密克戎严重结局的有效性：加拿大免疫研究网络研究。
Effectiveness of mRNA COVID-19 Monovalent and Bivalent Vaccine Booster Doses Against Omicron Severe Outcomes Among Adults Aged ≥50 Years in Ontario, Canada: A Canadian Immunization Research Network Study.
机构信息
Public Health Ontario, Toronto.
Dalla Lana School of Public Health, University of Toronto.
出版信息
J Infect Dis. 2024 Feb 14;229(2):394-397. doi: 10.1093/infdis/jiad419.
Abstract
We estimated the effectiveness of booster doses of monovalent and bivalent mRNA COVID-19 vaccines against Omicron-associated severe outcomes among adults aged ≥50 years in Ontario, Canada. Monovalent and bivalent mRNA COVID-19 booster doses provided similar strong initial protection against severe outcomes. Uncertainty remains around waning of protection from these vaccines.
摘要
我们评估了在加拿大安大略省，针对 50 岁及以上成年人，单价和双价 mRNA COVID-19 疫苗加强针针对奥密克戎相关重症结局的有效性。单价和双价 mRNA COVID-19 加强针对重症结局提供了类似的强大初始保护。这些疫苗的保护作用减弱仍存在不确定性。
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