Shelke Yogendra P, Bankar Nandkishor J, Bandre Gulshan R, Hawale Dattu V, Dawande Pratibha
Microbiology, Bhaktshreshtha Kamalakarpant Laxmanrao Walawalkar Rural Medical College, Sawarda, IND.
Microbiology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2023 Sep 4;15(9):e44666. doi: 10.7759/cureus.44666. eCollection 2023 Sep.
The rise of antimicrobial resistance (AMR) is a major global public health threat due to excessive and inappropriate use of antibiotics and is responsible for prolonged illness, longer hospital stays, and economic burden to society. This article aims to review the factors, role of antimicrobial stewardship, preventive strategies, and role of various organizations in combating AMR. Three major factors of AMR are inappropriate and excessive utilization of antibiotics, nonadherence to infection control measures, and the emergence of pathogens that are resistant to multiple drugs. Antimicrobial stewardship initiatives play a vital role in promoting judicious and targeted utilization of antimicrobials, thereby safeguarding their efficacy and mitigating the emergence of resistance. Implementing such programs optimizes patient outcomes by ensuring that individuals receive the most suitable therapeutic interventions. International organizations have a vital role to play in addressing AMR by promoting the responsible use of antimicrobials, developing new drugs, and improving surveillance systems. As AMR's impact grows, it is critical to take a collaborative and interdisciplinary approach to mitigate its consequences effectively.
由于抗生素的过度和不当使用,抗菌药物耐药性(AMR)的上升成为全球主要的公共卫生威胁,它导致疾病持续时间延长、住院时间增加,并给社会带来经济负担。本文旨在综述抗菌药物耐药性的影响因素、抗菌药物管理的作用、预防策略以及各组织在抗击抗菌药物耐药性方面的作用。抗菌药物耐药性的三个主要因素是抗生素的不当和过度使用、不遵守感染控制措施以及对多种药物耐药的病原体的出现。抗菌药物管理举措在促进抗菌药物的合理和有针对性使用方面发挥着至关重要的作用,从而维护其疗效并减少耐药性的出现。实施此类计划可通过确保个体接受最合适的治疗干预措施来优化患者治疗效果。国际组织在应对抗菌药物耐药性方面发挥着至关重要的作用,包括促进抗菌药物的合理使用、研发新药以及改善监测系统。随着抗菌药物耐药性影响的扩大,采取协作和跨学科方法以有效减轻其后果至关重要。