Weber Courtney, Hung Joseph, Atkins Emily R, Hickling Siobhan, Briffa Tom, Li Ian
School of Population and Global Health, The University of Western Australia, Perth, WA, Australia.
Medical School, The University of Western Australia, Perth, WA, Australia.
Heart Lung Circ. 2024 Jan;33(1):55-64. doi: 10.1016/j.hlc.2023.12.004. Epub 2023 Dec 29.
This study aimed to determine total and cardiovascular-specific re-hospitalisation patterns and associated costs within 2 years of index atrial fibrillation (AF) admission in Western Australia (WA).
Patients aged 25-94 years, surviving an index (first-in-period) AF hospitalisation (principal diagnosis) from 2011 to 2015 were identified from WA-linked administrative data and followed for 2 years. Person-level hospitalisation costs ($ Australian dollar) were computed using the Australian Refined Diagnosis Related Groups and presented as median with first and third quartile costs.
The cohort comprised 17,080 patients, 59.0% men, mean age 69.6±13.3 (standard deviation) years, and 59.0% had a CHADS-VA (one point for congestive heart failure, hypertension, diabetes mellitus, vascular disease or age 65-74 years; two points for prior stroke/transient ischaemic attack or age ≥75 years) score of 2 or more. Within 2 years, 13,776 patients (80.6%) were readmitted with median of 2 (1-4) readmissions. Among total all-cause readmissions (n=54,240), 40.1% were emergent and 36.6% were cardiovascular-related, led by AF (19.5%), coronary events (5.8%), and heart failure (4.2%). The median index AF admission cost was $3,264 ($2,899-$7,649) while cardiovascular readmission costs were higher, particularly stroke ($10,732 [$4,179-23,390]), AF ablation ($7,884 [$5,283-$8,878]), and heart failure ($6,759 [$6,081-$13,146]). Average readmission costs over 2 years per person increased by $4,746 (95% confidence interval [CI] $4,459-$5,033) per unit increase in baseline CHADS-VA score. The average 2-year hospitalisation costs per patient, including index admission, was $27,820 (95% CI $27,308-$28,333) and total WA costs were $475.2 million between 2011 and 2017.
Patients after index AF hospitalisation have a high risk of cardiovascular and other readmissions with considerable healthcare cost implications. Readmission costs increased progressively with baseline CHADS-VA score. Better integrated management of AF and coexistent comorbidities is likely key to reducing readmissions and associated costs.
本研究旨在确定西澳大利亚州(WA)首次房颤(AF)入院后2年内的全因再入院模式及心血管疾病特异性再入院模式,并计算相关费用。
从WA相关行政数据中识别出2011年至2015年期间首次(同期首次)因AF住院(主要诊断)且年龄在25 - 94岁之间的存活患者,并对其进行为期2年的随访。使用澳大利亚精细化诊断相关分组计算个体层面的住院费用(澳元),并以中位数以及第一和第三四分位数费用呈现。
该队列包括17,080名患者,男性占59.0%,平均年龄69.6±13.3(标准差)岁,59.0%的患者CHADS - VA(充血性心力衰竭、高血压、糖尿病、血管疾病或年龄在65 - 74岁计1分;既往卒中/短暂性脑缺血发作或年龄≥75岁计2分)评分≥2分。在2年内,13,776名患者(80.6%)再次入院,再入院中位数为2次(1 - 4次)。在所有全因再入院病例(n = 54,240)中,40.1%为急诊,36.6%与心血管疾病相关,其中以AF(19.5%)、冠状动脉事件(5.8%)和心力衰竭(4.2%)为主。首次AF入院的中位数费用为3,264澳元(2,899 - 7,649澳元),而心血管疾病再入院费用更高,尤其是卒中(10,732澳元[4,179 - 23,390澳元])、AF消融(7,884澳元[5,283 - 8,878澳元])和心力衰竭(6,759澳元[6,081 - 13,146澳元])。基线CHADS - VA评分每增加一个单位,每人2年的平均再入院费用增加4,746澳元(95%置信区间[CI] 4,459 - 5,033澳元)。每位患者包括首次入院在内的2年平均住院费用为27,820澳元(95% CI 27,308 - 28,333澳元),2011年至2017年期间WA的总费用为4.752亿澳元。
首次AF住院后的患者有较高的心血管疾病及其他再入院风险,对医疗保健费用有重大影响。再入院费用随基线CHADS - VA评分逐渐增加。更好地综合管理AF及并存的合并症可能是减少再入院及相关费用的关键。