Lung Cancer Center, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University.
Tohoku J Exp Med. 2024 Mar 16;262(3):201-209. doi: 10.1620/tjem.2023.J105. Epub 2023 Dec 28.
This study aimed to assess the impact of enhanced recovery after surgery (ERAS) intervention in preventing venous thromboembolism (VTE) among postoperative lung cancer patients. Conducted from January 2022 to January 2023, the research involved 125 lung cancer patients randomly assigned to either a control group (n = 60) receiving routine care, or an ERAS group (n = 65) which received both routine care and ERAS interventions. The ERAS program comprised a comprehensive series of interventions meticulously implemented throughout the preoperative, intraoperative, and postoperative phases. Thrombotic risk assessment using the Caprini Risk Assessment Model (RAM) was conducted preoperatively and on postoperative day 5 (POD 5), with plasma D-dimer levels measured preoperatively, on POD 1, POD 3, and POD 5. Quality of life and patient satisfaction were assessed at discharge using the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Lung Cancer Module 13 (QLQ-LC13) and The Newcastle Satisfaction with Nursing Scale (NSNS), respectively. The ERAS group demonstrated significantly lower Caprini RAM scores on POD 5 compared to the control group, with lower D-dimer levels on POD 3 and POD 5. The incidence of VTE was lower in the ERAS group (1.54%) compared to the control group (11.67%) during hospitalization. At discharge, the ERAS group showed improved quality of life, with higher satisfaction scores for nursing care and their hospital stay. ERAS nursing interventions effectively mitigate thrombotic risk, improve D-dimer levels, enhance postoperative quality of life, and elevate patient satisfaction among individuals undergoing lung cancer surgery.
本研究旨在评估术后强化康复(ERAS)干预对预防肺癌术后静脉血栓栓塞症(VTE)的影响。该研究于 2022 年 1 月至 2023 年 1 月进行,共纳入 125 例肺癌患者,随机分为对照组(n=60)和 ERAS 组(n=65)。对照组接受常规护理,ERAS 组在常规护理的基础上接受 ERAS 干预。ERAS 方案包括一系列术前、术中和术后精心实施的综合干预措施。使用 Caprini 风险评估模型(RAM)对患者进行术前和术后第 5 天(POD5)的血栓风险评估,并在术前、POD1、POD3 和 POD5 测量血浆 D-二聚体水平。采用欧洲癌症研究与治疗组织(EORTC)肺癌模块 13(QLQ-LC13)和纽卡斯尔护理满意度量表(NSNS)分别在出院时评估患者的生活质量和满意度。与对照组相比,ERAS 组患者在 POD5 的 Caprini RAM 评分显著降低,D-二聚体水平在 POD3 和 POD5 也更低。ERAS 组住院期间 VTE 发生率(1.54%)低于对照组(11.67%)。出院时,ERAS 组患者生活质量得到改善,护理满意度和住院时间评分更高。ERAS 护理干预可有效降低血栓风险,改善 D-二聚体水平,提高术后生活质量,提升患者满意度。