De Luca Daniele, Pezza Lucilla, Vivalda Laura, Di Nardo Matteo, Lepainteur Margaux, Baraldi Eugenio, Piastra Marco, Ricciardi Walter, Conti Giorgio, Gualano Maria Rosaria
Division of Paediatrics and Neonatal Critical Care, "A. Béclère" Hospital, APHP-Paris Saclay University, Paris, France.
Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris Saclay University, Paris, France.
EClinicalMedicine. 2024 Feb 1;69:102450. doi: 10.1016/j.eclinm.2024.102450. eCollection 2024 Mar.
Large seasonal outbreaks of bronchiolitis put pressure on healthcare systems and particularly on intensive care units (ICUs). ICU admission is necessary to provide respiratory support to the severest cases, otherwise bronchiolitis can result in substantial mortality. ICU resources are often insufficient and there is scant evidence to guide the ICU clinical management. Most available studies do not cover the ICU-admitted cases and do not consider the associated public health issues. We review this topic through a multidisciplinary approach from both the clinical and public health perspectives, with an analysis based on pathophysiology and cost-effectiveness. We suggest ways to optimise respiratory care, minimise ICU stay, "protect" ICU beds and, whenever possible, make them available for other critically ill children. We also provide guidance on how to prepare ICUs to work under stressful conditions due to outbreaks and to reduce the risk of nosocomial cross-contamination, particularly in ICUs caring for high-risk children.
None.
毛细支气管炎的大规模季节性暴发给医疗系统带来压力,尤其是对重症监护病房(ICU)。对于最严重的病例,有必要入住ICU以提供呼吸支持,否则毛细支气管炎可能导致相当高的死亡率。ICU资源往往不足,且几乎没有证据可指导ICU的临床管理。大多数现有研究未涵盖入住ICU的病例,也未考虑相关的公共卫生问题。我们从临床和公共卫生两个角度通过多学科方法对这一主题进行综述,并基于病理生理学和成本效益进行分析。我们提出优化呼吸护理、尽量缩短ICU住院时间、“保护”ICU床位并尽可能使其可供其他危重症儿童使用的方法。我们还就如何使ICU做好应对因暴发而产生的压力状况的准备以及降低医院内交叉污染风险提供指导,尤其是在照顾高危儿童的ICU中。
无。