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[糖尿病对血脂异常患者心血管风险的影响]

[Impact of diabetes on cardiovascular risk in patients with dyslipidemia].

作者信息

Peña-Rodríguez Gregorio, Gallardo-Hernández Ana G, Llerena-García Cindy G, Maldonado-Burgos Martha A, Escobedo-Naurisa Eloísa

机构信息

Medicina Familiar, Unidad de Medicina Familiar 48, Instituto Mexicano del Seguro Social, Ciudad Juárez, Chihuahua, Chih., México.

Unidad de Investigación Médica en Enfermedades Metabólicas, Siglo XXI, Coordinación de Investigación, Instituto Mexicano del Seguro Social, Ciudad de México, México.

出版信息

Arch Cardiol Mex. 2024 Feb 12;94(2):161-168. doi: 10.24875/ACM.23000042.

Abstract

OBJECTIVE

To determine the impact of diabetes on cardiovascular risk in patients with dyslipidemia.

METHOD

Observational, cross-sectional and comparative study in which cardiovascular risk was determined at 10 years in 100 patients with dyslipidemia, of these, 50 non-diabetic patients and 50 diabetic patients.

RESULTS

Both groups had similar characteristics in terms of age, blood pressure figures, average body mass index, and HDL and LDL levels. It was observed that the diabetic group has almost double the risk compared to the dyslipidemia group, 13.7 vs. 7.9 (p = 0.014), and the calculated heart age is also higher in patients with diabetes, 80 vs. 66 years (p = 0.003). Even in patients with diabetes there is a greater difference between the real age and the age of the heart, 24 years vs. 15 years of patients without diabetes (p = 0.000).

CONCLUSION

Having diabetes and dyslipidemia doubles the cardiovascular risk of patients. Little metabolic control was found in the population studied, which significantly increases complications at an early age and the economic burden on the health system and the families of patients, so it is necessary to rethink treatment strategies to improve metabolic control and with it the prognosis for the patient in the long term.

摘要

目的

确定糖尿病对血脂异常患者心血管风险的影响。

方法

进行观察性、横断面和对比研究,对100例血脂异常患者进行10年心血管风险测定,其中50例非糖尿病患者和50例糖尿病患者。

结果

两组在年龄、血压数值、平均体重指数以及高密度脂蛋白和低密度脂蛋白水平方面具有相似特征。观察发现,糖尿病组的风险几乎是非血脂异常组的两倍,分别为13.7和7.9(p = 0.014),糖尿病患者计算得出的心脏年龄也更高,分别为80岁和66岁(p = 0.003)。即使在糖尿病患者中,实际年龄与心脏年龄之间的差异也更大,糖尿病患者为24岁,非糖尿病患者为15岁(p = 0.000)。

结论

患有糖尿病和血脂异常会使患者的心血管风险加倍。在所研究的人群中发现代谢控制不佳,这显著增加了早年并发症以及卫生系统和患者家庭的经济负担,因此有必要重新思考治疗策略,以改善代谢控制,从而从长远上改善患者的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17f9/11160545/88f0d7e3b844/10125AMEX242-ACM-94-161-g001.jpg

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