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海藻中的化感物质及其生物勘探潜力。

Allelochemicals from the seaweeds and their bioprospecting potential.

机构信息

Biological Oceanography Division, CSIR-National Institute of Oceanography, Panaji, Goa, India, 403004.

Chemical Oceanography Division, CSIR-National Institute of Oceanography, Panaji, Goa, India, 403004.

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug;397(8):5387-5401. doi: 10.1007/s00210-024-03002-0. Epub 2024 Feb 23.

Abstract

Allelochemicals are secondary metabolites which function as a natural protection against grazing activities by algae and higher plants. They are one of the major metabolites engaged in the interactions of organisms. The chemically mediated interactions between organisms significantly influence the functioning of the ecosystems. Most of these compounds are secondary metabolites comprising sterols, terpenes, and polyphenols. These compounds not only play a defensive role, but also exhibit biological activities such as antioxidants, anti-cancer, anti-diabetes, anti-inflammation, and anti-microbial properties. This review article discusses the current understanding of the allelochemicals of seaweeds and their bioprospecting potential that can bring benefit to humanity. Specifically, the bioactive substances having specific health benefits associated with the consumption or application of seaweed-derived compounds. The properties of such allelochemicals can have implications for bioprospecting pharmaceutical, nutraceutical and cosmetic applications.

摘要

化感物质是作为藻类和高等植物天然防御放牧活动的次生代谢物。它们是参与生物相互作用的主要代谢物之一。生物体之间的化学介导相互作用显著影响生态系统的功能。这些化合物中的大多数是次生代谢物,包括甾醇、萜类化合物和多酚。这些化合物不仅具有防御作用,而且还具有生物活性,如抗氧化剂、抗癌、抗糖尿病、抗炎和抗菌特性。本文综述了海藻化感物质及其生物勘探潜力的最新研究进展,这将给人类带来益处。具体来说,具有特定健康益处的生物活性物质与海藻衍生化合物的食用或应用有关。这些化感物质的性质可能对药物、营养保健品和化妆品的生物勘探应用具有重要意义。

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