Suppr超能文献

乳糜泻的营养评估与管理。

Nutrition Assessment and Management in Celiac Disease.

机构信息

Department of Medicine, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.

Central Clinical School, Department of Gastroenterology, Monash University, Clayton, Victoria, Australia.

出版信息

Gastroenterology. 2024 Jun;167(1):116-131.e1. doi: 10.1053/j.gastro.2024.02.049. Epub 2024 Apr 7.

Abstract

Celiac disease (CeD) is the most common immune condition affecting the gastrointestinal tract; it is triggered by gluten and the only available treatment is a strict gluten-free diet (GFD). Therefore, for patients with CeD, adopting a GFD is not a lifestyle choice. The major problem is that a GFD is restrictive and, like all restrictive diets, it has the potential for adverse nutritional outcomes, especially if adopted for a long term. It is well known that GFD can be nutritionally inadequate and is frequently associated with vitamin and mineral deficiencies; it is also associated with excessive sugar and fat intake, particularly when gluten-free substitutes are consumed. Consequently, people with CeD are affected by higher rates of overweight and obesity and metabolic complications, such as fatty liver and cardiovascular disease. Therefore, assessment of nutritional status and diet quality at diagnosis and while on a long-term GFD is key in the management of CeD. This narrative review addresses nutritional considerations in CeD and management of common challenges associated with a GFD.

摘要

乳糜泻(CeD)是最常见的影响胃肠道的免疫性疾病;它是由麸质触发的,唯一可用的治疗方法是严格的无麸质饮食(GFD)。因此,对于 CeD 患者来说,采用 GFD 不是一种生活方式的选择。主要问题是 GFD 具有限制,并且与所有限制饮食一样,它有可能产生不良的营养结果,尤其是如果长期采用。众所周知,GFD 可能营养不足,并且经常与维生素和矿物质缺乏有关;它还与糖和脂肪摄入过多有关,尤其是当食用无麸质替代品时。因此,CeD 患者超重和肥胖以及代谢并发症的发生率更高,例如脂肪肝和心血管疾病。因此,在诊断时和长期 GFD 期间评估营养状况和饮食质量是 CeD 管理的关键。本综述讨论了 CeD 中的营养注意事项以及与 GFD 相关的常见挑战的管理。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验