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[慢性瘙痒患者的生活质量和睡眠质量]

[Quality of life and sleep quality in patients with chronic pruritus].

作者信息

Mann Caroline, Staubach Petra

机构信息

Haut- und Poliklinik der Johannes Gutenberg Universitätsmedizin Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.

出版信息

Dermatologie (Heidelb). 2024 Aug;75(8):612-616. doi: 10.1007/s00105-024-05373-0. Epub 2024 Jun 24.

Abstract

Pruritus is defined as a symptom that leads to scratching. Clinically, a heterogeneous group of clinical pictures of different etiology must be considered. Pruritus is characterized by varying intensity and duration. Many patients and/or their social environment, which is influenced by this, cite the impact on sleep quality as an accompanying main symptom. The patient's quality of life is affected depending on the severity of the pruritus and often leads to comorbidity such as depressive disorders or sleep disorders as well as to an impact on psychosocial well-being if it becomes chronic. To date, in addition to the medical history, the established examination methods have been the determination of the disease burden by assessing disease activity, e.g., with validated disease-specific scores, plus the assessment of quality of life using a dermatological quality of life index (DLQI). The latest studies show that this is by no means sufficient to determine the severity of disease and, as a result, to identify adequate treatment options.

摘要

瘙痒被定义为一种导致搔抓的症状。临床上,必须考虑不同病因的一组异质性临床症状。瘙痒的特点是强度和持续时间各不相同。许多患者和/或受此影响的社会环境将对睡眠质量的影响列为伴随的主要症状。患者的生活质量取决于瘙痒的严重程度,若瘙痒变为慢性,常导致合并症,如抑郁症或睡眠障碍,以及对心理社会幸福感产生影响。迄今为止,除病史外,既定的检查方法一直是通过评估疾病活动(例如使用经过验证的疾病特异性评分)来确定疾病负担,再加上使用皮肤病生活质量指数(DLQI)评估生活质量。最新研究表明,这远不足以确定疾病的严重程度,因此也无法确定适当的治疗方案。

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