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天然挥发青蒿素制备及在绿色杀虫剂中的应用。

Preparation and Application of Volatilized Wormwood Essence Derived Naturally into Green Insecticide.

机构信息

National Institute for Food and Drug Control, Beijing 100050, China.

School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China.

出版信息

Molecules. 2024 Jun 17;29(12):2877. doi: 10.3390/molecules29122877.

Abstract

Naturally occurring substances and their derivatives function as vital resources for pesticides that can be used in fields, such as insecticide production and fungicide development. As a botanical entity displaying multifaceted biological functions, wormwood has received thorough scrutiny across multiple sectors. The insect repellency potency combined with antibacterial and antifungal activities of wormwood position it as a potential candidate for prospective development into eco-friendly chemical pesticides. In this research, Wormwood essential oil was procured via ethanol water under ultrasonic scenarios and subsequently diluted with PEG 400 to formulate green chemical pesticides. The defensive efficacy of this green pesticide on plants was validated through 2 weeks of clustered plant growth experiments. Active constituents that exerted their effects were scrutinized by GC-MS. Furthermore, this green pesticide also displays efficacious effects on the prevention and management of aphids, exhibiting a dose-dependent relationship. 4-terpenol, eucalyptol, carvacrol, and L-borneol were identified by GC-MS as the predominant active constituents in this green chemical pesticide. Wormwood can be leveraged to develop green chemical pesticides, which can protect plants without contaminating the environment.

摘要

天然物质及其衍生物是农药的重要资源,可以用于农业领域,如杀虫剂生产和杀菌剂开发。作为一种具有多种生物功能的植物实体,艾草受到了多个领域的深入研究。艾草的驱虫功效以及其抗菌和抗真菌活性使其成为开发环保型化学农药的潜在候选物。在这项研究中,通过超声水乙醇法提取艾草精油,然后用 PEG400 稀释,制成绿色化学农药。通过 2 周的集群植物生长实验验证了这种绿色农药对植物的防治效果。通过 GC-MS 对发挥作用的活性成分进行了研究。此外,这种绿色农药对蚜虫的防治也有效果,表现出剂量依赖性。通过 GC-MS 鉴定出这种绿色化学农药中的主要活性成分有 4-萜醇、桉油醇、香芹酚和 L-龙脑。艾草可以被开发为绿色化学农药,保护植物而不污染环境。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc5/11206975/be911dc70d1d/molecules-29-02877-g001.jpg

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