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埃塞俄比亚极端生育年龄母亲所生新生儿的死亡率;对2016年埃塞俄比亚人口与健康调查数据的多水平混合效应分析

Mortality of neonates born to mothers of extreme reproductive age in Ethiopia; multilevel mixed effect analysis of Ethiopian demographic and health survey data of 2016.

作者信息

Tekeba Berhan, Techane Masresha Asmare, Workneh Belayneh Shetie, Zegeye Alebachew Ferede, Gonete Almaz Tefera, Alemu Tewodros Getaneh, Wassie Mulugeta, Kassie Alemneh Tadesse, Ali Mohammed Seid, Mekonen Enyew Getaneh, Tamir Tadesse Tarik

机构信息

Department of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Department of Emergency and Critical Care Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

Front Pediatr. 2024 Jun 28;12:1390952. doi: 10.3389/fped.2024.1390952. eCollection 2024.

Abstract

INTRODUCTION

Neonatal mortality is still a major public health problem in middle- and low-income countries like Ethiopia. Despite strategies and efforts made to reduce neonatal death, the mortality rate declines at a slower pace in the country. Though there are studies conducted on neonatal mortality and its determinants, our searches of the literature have found no study on the extent of mortality of neonates born to mothers of extreme reproductive age in the study area. Therefore, this study aimed to assess the magnitude and factors associated with the mortality of neonates born to mothers of extreme reproductive age in Ethiopia.

METHODS

Secondary data analysis was conducted using 2016 Ethiopian Demographic and Health Survey data. The final study contained an overall weighted sample of 2,269 live births. To determine the significant factors in newborn deaths, a multilevel binary logistic regression was fitted. For measuring the clustering impact, the intra-cluster correlation coefficient, median odds ratio, proportional change in variance, and deviation were employed for model comparison. The adjusted odds ratio with a 95% confidence interval was presented in the multivariable multilevel logistic regression analysis to identify statistically significant factors in neonatal mortality. A -value of less than 0.05 was declared statistically significant.

RESULTS

The neonatal mortality rate of babies born to extreme aged reproductive women in Ethiopia was 34 (95% Cl, 22.2%-42.23%) per 1,000 live birth. Being twin pregnancy (AOR = 10; 95% Cl: 8.61-20.21), being from pastoralist region (AOR = 3.9; 95% Cl: 1.71-8.09), having larger baby size (AOR = 2.93; 95% Cl: 1.4-9.12) increase the odds of neonatal mortality. On the other hand, individual level media exposure (AOR = 0.3; 95% Cl: 0.09-0.91) and community level media exposure (AOR = 0.24; 95% Cl: 0.07-0.83), being term gestation (AOR = 0.14; 95% Cl: 0.01-0.81) decreases the odds of neonatal mortality born to mothers of extreme reproductive age.

CONCLUSION

Ethiopia had a greater rate of neonatal death among babies born at the extremes of reproductive age than overall reproductive life. Multiple pregnancies, larger baby sizes, emerging regions, term gestation, and media exposure were found to be significant factors associated with the mortality of neonates born to mothers of extreme reproductive age. Therefore, the concerned bodies should give emphasis to mothers giving birth before the age of 20 and above 35, access to media, healthy pregnancy, and special attention to pastoralists to reduce the burden of neonatal mortality.

摘要

引言

在埃塞俄比亚这样的中低收入国家,新生儿死亡率仍是一个重大的公共卫生问题。尽管已采取各种策略和做出努力来降低新生儿死亡,但该国的死亡率下降速度仍较为缓慢。虽然有关于新生儿死亡率及其决定因素的研究,但我们对文献的检索发现,在研究区域内,尚无关于极端生育年龄母亲所生新生儿的死亡率情况的研究。因此,本研究旨在评估埃塞俄比亚极端生育年龄母亲所生新生儿的死亡规模及其相关因素。

方法

使用2016年埃塞俄比亚人口与健康调查数据进行二次数据分析。最终研究包含2269例活产的总体加权样本。为确定新生儿死亡的显著因素,拟合了多水平二元逻辑回归模型。为衡量聚类影响,采用聚类内相关系数、中位数优势比、方差的比例变化和偏差进行模型比较。在多变量多水平逻辑回归分析中呈现调整后的优势比及其95%置信区间,以确定新生儿死亡率的统计学显著因素。P值小于0.05被判定为具有统计学显著性。

结果

埃塞俄比亚极端生育年龄的母亲所生婴儿的新生儿死亡率为每1000例活产中有34例(95%置信区间,22.2% - 42.23%)。双胞胎妊娠(调整后优势比 = 10;95%置信区间:8.61 - 20.21)、来自牧区(调整后优势比 = 3.9;95%置信区间:1.71 - 8.09)、婴儿体型较大(调整后优势比 = 2.93;95%置信区间:1.4 - 9.12)会增加新生儿死亡的几率。另一方面,个人层面的媒体接触(调整后优势比 = 0.3;95%置信区间:0.09 - 0.91)和社区层面的媒体接触(调整后优势比 = 0.24;95%置信区间:0.07 - 0.83)、足月妊娠(调整后优势比 = 0.14;95%置信区间:0.01 - 0.81)会降低极端生育年龄母亲所生新生儿的死亡几率。

结论

埃塞俄比亚极端生育年龄出生的婴儿的新生儿死亡率高于整个生育期的总体水平。多胎妊娠、婴儿体型较大、新兴地区、足月妊娠和媒体接触被发现是与极端生育年龄母亲所生新生儿死亡率相关的显著因素。因此,相关机构应重视20岁之前和35岁以上生育的母亲、媒体接触机会、健康妊娠,并特别关注牧民,以减轻新生儿死亡负担。

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