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2010年至2022年丹麦15至24岁人群的全因死亡率和特定原因死亡率:社会经济预测因素的全国性研究

All cause and cause specific mortality in 15-24-year-olds in Denmark 2010 to 2022: nationwide study of socioeconomic predictors.

作者信息

Kruckow Sofie, Tolstrup Janne S

机构信息

National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

出版信息

BMJ Med. 2024 Aug 16;3(1):e000685. doi: 10.1136/bmjmed-2023-000685. eCollection 2024.

Abstract

OBJECTIVE

To assess inequalities in all cause and cause specific mortality in young people and if there are differences across gender and age groups.

DESIGN

Nationwide cohort study of socioeconomic predictors.

SETTING

Denmark, 1 January 2010 to 31 December 2022.

PARTICIPANTS

All Danes of ages 15 to 24 years during the study period summing to a total of 9 314 807 person years and 2297 deaths. Participant and parental information were linked to obtain information on socioeconomic background to investigate differences in parents' educational level, employment status, and family's disposable income, using annually updated nationwide registers.

MAIN OUTCOME MEASURES

All cause and cause specific mortality including natural deaths (ie, medical conditions and diseases) and unnatural deaths (accidents, suicides, and homicides). Poisson regression was used to calculate incidence rate ratios and 95% confidence intervals (CI).

RESULTS

Overall mortality rate was 24.7 (95% CI 23.7 to 25.7) and higher for men (33.2 (31.5 to 34.8)) compared with women (15.8 (14.6 to 16.9)). All cause and cause specific mortality were higher in financially disadvantaged groups compared with more affluent groups, and consistently so for all three measures of socioeconomic position. Results generally reflected a dose dependent association showing a higher mortality with lower levels of socioeconomic position. For instance, incidence rate ratios of all cause mortality related to parents' education was 2.3 (95% CI 2.0 to 2.7) for elementary level, 1.5 (1.3 to 1.6) for low, and 1.3 (1.1 to 1.4) for medium level as compared with high level. For deaths, incidence rate ratios of elementary education level compared with the most well educated group were 2.2 (1.5 to 3.2) for natural causes, 3.3 (2.5 to 4.4) for accidents, 1.6 (1.2 to 2.2) for suicides, and 3.1 (0.8 to 12) for homicides. Associations were similar in strata of men and women and by age group (15-17 18-24 years). Mortality in young men was considerably higher than in young women for all of the causes.

CONCLUSION

Young people from disadvantaged backgrounds have a markedly higher mortality from all causes than those from more affluent families. The socioeconomic position of their parents was associated with premature mortality in a dose dependent manner meaning that this effect is not only a concern for marginalised groups. Public health attention should be directed to respond to these inequities by strengthening advocacy for adolescent health, ensuring focus on adolescents in health policies and strategies, using the response to adolescent health as an indicator of equity, and prioritising research into the underlying mechanisms linking socioeconomic position in adolescence and mortality.

摘要

目的

评估年轻人全因死亡率和特定病因死亡率的不平等情况,以及不同性别和年龄组之间是否存在差异。

设计

关于社会经济预测因素的全国队列研究。

背景

丹麦,2010年1月1日至2022年12月31日。

参与者

研究期间所有年龄在15至24岁的丹麦人,总计9314807人年,2297例死亡。参与者和父母的信息相链接,以获取社会经济背景信息,通过每年更新的全国登记册来调查父母的教育水平、就业状况和家庭可支配收入的差异。

主要观察指标

全因死亡率和特定病因死亡率,包括自然死亡(即疾病和病症)和非自然死亡(事故、自杀和杀人)。采用泊松回归计算发病率比和95%置信区间(CI)。

结果

总体死亡率为24.7(95%CI 23.7至25.7),男性(33.2(31.5至34.8))高于女性(15.8(14.6至16.9))。与较富裕群体相比,经济弱势群体的全因死亡率和特定病因死亡率更高,社会经济地位的所有三项衡量指标均一致如此。结果总体反映了一种剂量依赖性关联,即社会经济地位越低,死亡率越高。例如,与高水平相比,与父母教育相关的全因死亡率发病率比,小学水平为2.3(95%CI 2.0至2.7),低水平为1.5(1.3至1.6),中等水平为1.3(1.1至1.4)。对于死亡,与受教育程度最高的群体相比,小学教育水平的自然病因发病率比为2.2(1.5至3.2),事故为3.3(2.5至4.4),自杀为1.6(1.2至2.2),杀人为3.1(0.8至12)。在男性和女性分层以及按年龄组(15 - 17岁、18 - 24岁)中,关联相似。所有病因导致的年轻男性死亡率均显著高于年轻女性。

结论

来自弱势背景的年轻人全因死亡率明显高于来自较富裕家庭的年轻人。其父母的社会经济地位与过早死亡率呈剂量依赖性关联,这意味着这种影响不仅是边缘化群体所关注的问题。公共卫生应予以关注,通过加强对青少年健康的宣传倡导、确保在卫生政策和战略中关注青少年、将对青少年健康的应对作为公平性指标以及优先研究将青少年社会经济地位与死亡率联系起来的潜在机制,来应对这些不平等现象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab78/11340248/d96ad269aa5c/bmjmed-3-1-g001.jpg

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