在全国封锁以防止SARS-CoV-19传播期间的急性特发性心包炎
Acute idiopathic pericarditis during a national lockdown to prevent transmission of SARS-COVID-19.
作者信息
Langsted Anne, Edwards Nicola C, Pasley Tom, Stewart Ralph A H
机构信息
Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark.
Greenlane Cardiovascular Service, Auckland City Hospital, Te Whatu Ora - Health New Zealand, Te Toka Tumai, Auckland, New Zealand.
出版信息
Int J Cardiol Heart Vasc. 2024 Apr 4;53:101398. doi: 10.1016/j.ijcha.2024.101398. eCollection 2024 Aug.
BACKGROUND
Idiopathic acute pericarditis is often presumed to have a viral cause. We hypothesized that if acute viral infection was the cause, the incidence of acute 'idiopathic' pericarditis would decrease during a public health lockdown introduced to prevent the spread of SARS-COVID-19 in New Zealand when acute viral infections decreased by 75% to 99%.
METHODS
Hospitalization for acute 'idiopathic' pericarditis during 5 months of the national public health lockdown were compared to 54 months before the COVID-19 pandemic from administrative data.
RESULTS
The hospitalization rate for acute pericarditis was similar before (n = 1364, 24.8 cases/30 days) compared to during the public health lockdown (n = 132, 25.8 cases/30 days), +4% 95 % confidence interval -25 % to +30 % (P = 0.67).
CONCLUSION
These observations do not support the hypothesis that acute viral infection is the cause for most cases of acute idiopathic pericarditis.
背景
特发性急性心包炎通常被认为由病毒引起。我们推测，如果急性病毒感染是病因，那么在新西兰为预防SARS-CoV-19传播而实施的公共卫生封锁期间，当急性病毒感染减少75%至99%时，急性“特发性”心包炎的发病率将会降低。
方法
利用行政数据，将全国公共卫生封锁的5个月期间急性“特发性”心包炎的住院情况与新冠疫情大流行前的54个月进行比较。
结果
急性心包炎的住院率在公共卫生封锁前（n = 1364，24.8例/30天）与封锁期间（n = 132，25.8例/30天）相似，增加4%，95%置信区间为-25%至+30%（P = 0.67）。
结论
这些观察结果不支持急性病毒感染是大多数急性特发性心包炎病例病因这一假说。
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