Faculty of Ecotechnology, ITMO University, Saint Petersburg, Russian Federation.
Institute of Chemical Engineering, Ural Federal University, Yekaterinburg, Russian Federation.
Nutrition. 2025 Jan;129:112596. doi: 10.1016/j.nut.2024.112596. Epub 2024 Oct 10.
In recent times, there has been growing interest in understanding the factors contributing to prolonged and healthy lifespans observed in specific populations, tribes, or countries. Factors such as environmental and dietary play significant roles in shaping the ageing process and are often the focus of inquiries seeking to unravel the secrets behind longevity. Among these factors, diet emerges as a primary determinant, capable of either promoting or mitigating the onset of age-related diseases that impact the ageing trajectory. This review examines the impact of various diet types on ageing and age-related conditions, including cardiovascular disease, cancer, neurodegenerative disorders, and metabolic syndrome. Different dietary patterns, such as the Mediterranean diet, the Japanese diet, vegetarian and vegan diets, as well as low-carbohydrate and ketogenic diets, are evaluated for their potential effects on longevity and health span. Each diet type is characterized by distinct nutritional profiles, emphasizing specific food groups, macronutrient compositions, and bioactive components, which may exert diverse effects on ageing processes and disease risk. Additionally, dietary factors such as calorie restriction, intermittent fasting, and dietary supplementation are explored for their potential anti-ageing and disease-modifying effects. Understanding the influence of various diet types on ageing and age-related diseases can inform personalized dietary recommendations and lifestyle interventions aimed at promoting healthy aging and mitigating age-associated morbidities.
近年来,人们越来越关注了解特定人群、部落或国家中观察到的长寿和健康寿命的影响因素。环境和饮食等因素在塑造衰老过程中起着重要作用,往往是探究长寿背后秘密的重点。在这些因素中,饮食是一个主要的决定因素,它既能促进也能减缓与年龄相关的疾病的发生,这些疾病会影响衰老的轨迹。本综述探讨了各种饮食类型对衰老和与年龄相关的疾病的影响,包括心血管疾病、癌症、神经退行性疾病和代谢综合征。评估了地中海饮食、日本饮食、素食和纯素饮食以及低碳水化合物和生酮饮食等不同的饮食模式,它们对长寿和健康寿命的潜在影响。每种饮食类型都有其独特的营养特点,强调特定的食物组、宏量营养素组成和生物活性成分,这些可能对衰老过程和疾病风险产生不同的影响。此外,还探讨了热量限制、间歇性禁食和饮食补充等饮食因素对延缓衰老和疾病的潜在影响。了解各种饮食类型对衰老和与年龄相关的疾病的影响,可以为促进健康衰老和减轻与年龄相关的疾病提供个性化的饮食建议和生活方式干预。