Reuken Philipp A, Besteher Bianca, Bleidorn Jutta, Brockmann Dirk, Finke Kathrin, Freytag Antje, Lehmann-Pohl Katja, Lemhöfer Christiana, Mikolajczyk Rafael, Puta Christian, Scherag André, Wiedermann Marc, Zippel-Schultz Bettina, Stallmach Andreas
Department for Internal Medicine IV (Gastroenterology, Hepatology and Infectious Diseases), Jena University Hospital, Jena, Germany.
Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany.
Digit Health. 2024 Oct 14;10:20552076241291748. doi: 10.1177/20552076241291748. eCollection 2024 Jan-Dec.
After infection with SARS-CoV-2, a substantial proportion of patients develop long-lasting sequelae. These sequelae include fatigue (potentially as severe as that seen in ME/CFS cases), cognitive dysfunction, and psychiatric symptoms. Because the pathophysiology of these sequelae remains unclear, existing therapeutic concepts address the symptoms through pacing strategies, cognitive training, and psychological therapy.
Here, we present a protocol for a digital multimodal structured intervention addressing common symptoms through three intervention modules: BRAIN, BODY, and SOUL. This intervention includes an assessment conducted via a mobile "post-COVID-19 bus" near the patient's home, as well as the use of wearable devices and mobile applications to support pacing strategies and collection of data, including ecological momentary assessment.
We will focus on physical component subscore of the SF36 as Quality of Life parameter as the primary outcome parameter for WATCH to take into account the holistic approach that is necessary for care of post-COVID patients.
In the current project, we present a protocol for a holistic and multimodal structured therapeutic concept which is easily accessible, and scalable for post-COVID patients.
感染新型冠状病毒2(SARS-CoV-2)后,相当一部分患者会出现长期后遗症。这些后遗症包括疲劳(可能与肌痛性脑脊髓炎/慢性疲劳综合征患者所见的一样严重)、认知功能障碍和精神症状。由于这些后遗症的病理生理学仍不清楚,现有的治疗理念通过调整节奏策略、认知训练和心理治疗来解决症状。
在此,我们提出了一种数字多模式结构化干预方案,通过三个干预模块:大脑(BRAIN)、身体(BODY)和心灵(SOUL)来解决常见症状。这种干预包括通过患者家附近的移动“新冠后巴士”进行评估,以及使用可穿戴设备和移动应用程序来支持节奏调整策略和数据收集,包括生态瞬时评估。
作为生活质量参数,我们将重点关注SF36的身体成分评分,作为WATCH的主要结局参数,以考虑新冠后患者护理所需的整体方法。
在当前项目中,我们提出了一种整体且多模式的结构化治疗理念方案,该方案易于获取,且可扩展用于新冠后患者。