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使用可弯曲且可导航的输尿管吸引鞘评估下极结石与非下极结石的软性输尿管镜检查结果:欧洲泌尿外科学会腔内泌尿外科和PEARLS小组的一项前瞻性多中心研究

Assessing flexible ureteroscopy outcomes for lower Pole versus non lower Pole stones using the flexible and navigable suction ureteric access sheath: a prospective multicenter study by EAU Endourology and PEARLS group.

作者信息

Shrestha Anil, Traxer Olivier, Seitz Christian, Corrales Mariela, Castellani Daniele, Chew Ben Hall, Ragoori Deepak, Mishra Udita, Hamri Saeed Bin, Tan Karl Marvin, Yuen Steffi Kar Kei, Chitrakar Akash, Keller Etienne Xavier, Somani Bhaskar Kumar, Gauhar Vineet

机构信息

Department of Urology, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.

Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.

出版信息

World J Urol. 2024 Dec 20;43(1):41. doi: 10.1007/s00345-024-05384-5.

Abstract

PURPOSE

Use of suction in flexible ureteroscopy is increasing lately. The introduction of flexible and navigable suction access sheath (FANS) has shown improved stone free rate (SFR). However, its efficacy in lower pole stone (LPS) in terms of SFR and complications is yet to be studied.

METHODS

We collected data from 25 centers that included 394 adult patients undergoing ureteroscopy using FANS. Non contrast CT (NCCT) scan was done within first 30 days post operatively to access the SFR. Residual fragments were graded as A: 100% SFR; B: single fragment ≤ 2 mm; C: single fragment 2.1-4 mm; D: Single or multiple fragments > 4 mm. Post operative complications were recorded.

RESULTS

Out of 394 patients, non LPS (group1) comprised of 268 patients, rest 126 patients had LPS (group 2). Single stage zero fragment SFR was seen in 58.6% (group 1) vs. 54.8% (group 2) (P = 0.619). Single stage grade A + B SFR was achieved in 96.6% vs. 98.4% in groups 1 and 2 respectively. On multivariate analysis Thulium fiber laser use was significantly associated with higher odds of being grade A stone-free, while stone volume with lower odds. In LPS group only two patients needed reintervention. The highest grade of complication was Clavien 2, which was seen in 3.2% LPS group.

CONCLUSION

Use of flexible and navigable suction ureteric access sheath for lower pole stones is effective and safe. The stone free rate of lower pole stones is comparable to non-lower pole locations with very low reintervention rate in both groups.

摘要

目的

近年来,软性输尿管镜术中吸引技术的应用日益增多。可弯曲可导航吸引鞘(FANS)的引入提高了无石率(SFR)。然而,其在处理下极结石(LPS)方面的疗效,包括无石率和并发症,仍有待研究。

方法

我们收集了来自25个中心的数据,包括394例使用FANS进行输尿管镜检查的成年患者。术后30天内进行非增强CT(NCCT)扫描以评估无石率。残留碎片分为:A:100%无石;B:单个碎片≤2mm;C:单个碎片2.1 - 4mm;D:单个或多个碎片>4mm。记录术后并发症。

结果

394例患者中,非下极结石患者(第1组)268例,其余126例为下极结石患者(第2组)。第1组单期零碎片无石率为58.6%,第2组为54.8%(P = 0.619)。第1组和第2组单期A + B级无石率分别为96.6%和98.4%。多因素分析显示,使用铥光纤激光与A级无石的较高几率显著相关,而结石体积与较低几率相关。在下极结石组中,仅2例患者需要再次干预。最高级别的并发症为Clavien 2级,在下极结石组中的发生率为3.2%。

结论

使用可弯曲可导航吸引输尿管鞘处理下极结石是有效且安全的。下极结石的无石率与非下极结石部位相当,两组的再次干预率都很低。

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