2型糖尿病认知障碍的叙述性综述：全球趋势与诊断方法
A Narrative Review on Cognitive Impairment in Type 2 Diabetes: Global Trends and Diagnostic Approaches.
作者信息
Liao Xiaobin, Zhang Yibin, Xu Jialu, Yin Jiaxin, Li Shan, Dong Kun, Shi Xiaoli, Xu Weijie, Ma Delin, Chen Xi, Yu Xuefeng, Yang Yan
机构信息
Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Second Clinical College, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
出版信息
Biomedicines. 2025 Feb 14;13(2):473. doi: 10.3390/biomedicines13020473.
Diabetes is a chronic disease that affects many people, with both its incidence and prevalence rising globally. Diabetes can lead to various complications, among which cognitive impairment in diabetic patients significantly impacts their daily life and blood glucose management, complicating treatment and worsening prognosis. Therefore, the early diagnosis and treatment of cognitive impairment are essential to ensure the health of diabetic patients. However, there is currently no widely accepted and effective method for the early diagnosis of diabetes-related cognitive impairment. This review aims to summarize potential screening and diagnostic methods, as well as biomarkers, for cognitive impairment in diabetes, including retinal structure and function examination, brain imaging, and peripheral blood biomarkers, providing valuable information and support for clinical decision making and future research.
糖尿病是一种影响众多人群的慢性疾病，其发病率和患病率在全球范围内都呈上升趋势。糖尿病可导致多种并发症，其中糖尿病患者的认知障碍会对其日常生活和血糖管理产生显著影响，使治疗复杂化并恶化预后。因此，认知障碍的早期诊断和治疗对于确保糖尿病患者的健康至关重要。然而，目前尚无广泛接受且有效的方法用于早期诊断糖尿病相关的认知障碍。本综述旨在总结糖尿病认知障碍的潜在筛查和诊断方法以及生物标志物，包括视网膜结构和功能检查、脑成像以及外周血生物标志物，为临床决策和未来研究提供有价值的信息和支持。
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