一名呼吸道合胞病毒与化脓性链球菌合并感染儿童的重症类肺炎性胸腔积液
Severe Parapneumonic Effusion in a Child With Respiratory Syncytial Virus and Streptococcus pyogenes Coinfection.
作者信息
Sugita Hikaru, Miura Hiroki, Horiba Kazuhiro, Nakajima Yoichi, Yoshikawa Tetsushi
机构信息
Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, JPN.
Laboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases, Tokyo, JPN.
出版信息
Cureus. 2025 Feb 16;17(2):e79080. doi: 10.7759/cureus.79080. eCollection 2025 Feb.
A four-year-old boy with respiratory syncytial virus (RSV) infection and suspected bacterial coinfection deteriorated despite antibiotic treatment. Intensive care and thoracoscopic debridement were required due to parapneumonic effusion. Despite negative pleural fluid cultures, next-generation sequencing detected group A (GAS). Even in healthy children without risk factors, RSV infection preceding invasive GAS infection can rapidly deteriorate, making diagnosis difficult.
一名患有呼吸道合胞病毒（RSV）感染且疑似合并细菌感染的4岁男孩，尽管接受了抗生素治疗，病情仍恶化。由于肺炎旁胸腔积液，需要重症监护和胸腔镜清创术。尽管胸腔积液培养结果为阴性，但二代测序检测到A组链球菌（GAS）。即使在没有危险因素的健康儿童中，侵袭性GAS感染前的RSV感染也可能迅速恶化，导致诊断困难。
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