Rodriguez-Leal Cristobal M, González-Corralejo Carlos, Candel Francisco Javier, Salavert Miguel
Emergency Medicine Department, Hospital Universitario del Henares, Coslada, Madrid, Spain.
Emergency Research Group, Spanish Society of Emergency Medicine (INFURGSEMES-SEMES), Spain.
Rev Esp Quimioter. 2025 Mar 27;38(3):152-186. doi: 10.37201/req/017.2025.
Pneumonia is the leading cause of death from infection in the developed world. In recent years, researchers and healthcare professionals have worked extensively to reduce this burden. Prevention is better than cure, and significant advances have been made in areas such as vaccination and the prevention of nosocomial pneumonia in intensive care units. Comprehensive surveillance programmes and new diagnostic methods have been developed to assess trends in this disease and to identify the infectious agents involved. Clinical presentation can be challenging in elderly patients or those with certain comorbidities, prompting new studies in these populations to address these issues. Correct and early management of severe community-acquired pneumonia represents a major opportunity to reduce its associated mortality. Although fungal pathogens are an uncommon cause of lung infection, they are associated with high morbidity and mortality, highlighting the need for new approaches. Finally, new drugs are available for the treatment of pneumonia, and a thorough understanding of them is key to ensuring their correct use, particularly to combat multi-resistance. To provide an update on these points, a multidisciplinary team of Spanish experts convened at the Sixth Annual Meeting of Pneumonia Day, under the scientific sponsorship of GEIPC-SEIMC. This paper reflects the information shared at this meeting, offering the latest insights on these topics and supporting a holistic approach to pneumonia management.
在发达国家,肺炎是感染性疾病致死的首要原因。近年来,研究人员和医疗保健专业人员为减轻这一负担付出了巨大努力。预防胜于治疗,在疫苗接种和重症监护病房医院获得性肺炎的预防等领域已取得显著进展。已制定了综合监测方案和新的诊断方法,以评估该疾病的趋势并确定相关的感染病原体。老年患者或患有某些合并症的患者的临床表现可能具有挑战性,这促使针对这些人群开展新的研究以解决这些问题。正确且早期管理重症社区获得性肺炎是降低其相关死亡率的一个重大契机。尽管真菌病原体是肺部感染的罕见病因,但它们与高发病率和高死亡率相关,这凸显了采用新方法的必要性。最后,有了治疗肺炎的新药,全面了解这些药物是确保正确使用它们的关键,特别是应对多重耐药性。为了就这些要点提供最新信息,西班牙专家多学科团队在肺炎日第六届年会上召开会议,由西班牙医院感染和临床微生物学会(GEIPC-SEIMC)提供科学赞助。本文反映了本次会议上分享的信息,提供了关于这些主题的最新见解,并支持对肺炎管理采取整体方法。