Ravnkilde Ditte Maria, Horsten Laura Speich, Møller Ann Merete
Department of Anaesthesiology, Herlev and Gentofte Hospital, Herlev, Denmark.
Department of Clinical Medicine, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark.
Acta Anaesthesiol Scand. 2025 Jul;69(6):e70043. doi: 10.1111/aas.70043.
Childbirth is often a profoundly painful experience for women. The World Health Organization (WHO) recommends epidural analgesia or opioids as primary pharmacological pain management options for labor. However, many other methods of analgesia are available today, although they have different evidence backgrounds. This scoping review will map the literature on these pharmacological pain management methods for vaginal childbirth, examining their effectiveness, risks, and side effects to provide a comprehensive overview.
The scoping review will be conducted in accordance with the JBI methodology and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) checklist. A broad systematic search will be performed across multiple databases, including a backward citation search of the included articles. Data extraction will include study characteristics, population characteristics, analgesia type, and outcomes.
The results will be presented using a narrative synthesis as well as descriptive statistics in tables, figures, or graphs as appropriate.
The scoping review aims to map the newest existing knowledge on pharmacological pain management for women during labor. Furthermore, we will identify research gaps in this area to help shape the direction for future research.
分娩对女性来说往往是一段极其痛苦的经历。世界卫生组织(WHO)推荐硬膜外镇痛或阿片类药物作为分娩时主要的药物性疼痛管理选择。然而,如今还有许多其他镇痛方法,尽管它们有着不同的证据背景。本综述将梳理关于这些阴道分娩药物性疼痛管理方法的文献,考察其有效性、风险及副作用,以提供全面概述。
本综述将按照循证卫生保健国际协作组(JBI)方法及系统评价与Meta分析扩展版的范围综述优先报告条目(PRISMA-ScR)清单进行。将在多个数据库中进行广泛的系统检索,包括对纳入文章进行逆向引文检索。数据提取将包括研究特征、人群特征、镇痛类型及结果。
结果将采用叙述性综合呈现,并酌情以表格、图表形式展示描述性统计数据。
本综述旨在梳理关于女性分娩时药物性疼痛管理的最新现有知识。此外,我们将识别该领域的研究空白,以助力确定未来研究方向。