Appleby Sara, Al Musaimi Othman
School of Pharmacy, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UK.
Int J Environ Res Public Health. 2025 May 9;22(5):750. doi: 10.3390/ijerph22050750.
Concerns sparked by the US opioid epidemic have led to increased attempts to reduce England's overall opioid consumption. Variations in health literacy across the country have led to differing prescribing practices, with increased chronic conditions appearing in areas of increased socioeconomic deprivation. This review investigated the relationship between increased opioid utilization and increased socioeconomic deprivation, aiming to highlight areas of England which have the highest opioid consumption. The review has investigated a range of socioeconomic factors, such as unemployment and fuel poverty, which have consequently influenced the higher frequency of opioid prescribing in areas where these factors were highest. Opioid abuse was most prevalent in areas with higher levels of deprivation. Geographically, areas with the highest levels of deprivation, and consequent opioid consumption, were situated in the North of England, with cities like London having a significantly lower consumption rate in comparison. These trends are a good starting point when designing future opioid epidemic-prevention strategies, as specific areas can be targeted to propel a reduction in opioid prescribing and addiction and thus decrease the likelihood of an opioid crisis forming. Although a longitudinal study would have strengthened the findings of this review, it was not feasible due to practical constraints.
美国阿片类药物泛滥引发的担忧促使人们加大了降低英国总体阿片类药物消费量的努力。全国各地健康素养的差异导致了不同的处方做法,社会经济贫困加剧地区的慢性病发病率也有所上升。本综述调查了阿片类药物使用增加与社会经济贫困加剧之间的关系,旨在找出英国阿片类药物消费量最高的地区。该综述研究了一系列社会经济因素,如失业和燃料贫困,这些因素进而影响了在这些因素最为严重的地区阿片类药物处方开具频率较高的情况。阿片类药物滥用在贫困程度较高的地区最为普遍。从地理位置来看,贫困程度最高且阿片类药物消费量随之最高的地区位于英格兰北部,相比之下,像伦敦这样的城市的消费率则显著较低。这些趋势是设计未来阿片类药物泛滥预防策略的良好起点,因为可以针对特定地区来推动阿片类药物处方开具量和成瘾率的降低,从而减少阿片类药物危机形成的可能性。尽管纵向研究本可加强本综述的研究结果,但由于实际限制,这并不可行。