使用秀丽隐杆线虫测量健康参数的检测方法简要指南。
Brief guide to assays for measuring health parameters using Caenorhabditis elegans.
作者信息
Hwang Seungjae, Lee Jongsun, Lee Seung-Jae V
机构信息
Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
出版信息
Mol Cells. 2025 May 26;48(8):100233. doi: 10.1016/j.mocell.2025.100233.
Assessing health parameters is essential for understanding the decline of physiological functions during aging. The nematode Caenorhabditis elegans serves as a powerful model in aging research. This paper introduces representative methods for evaluating health parameters using C. elegans and provides quantitative indicators of functional declines during aging. This manuscript will be useful for researchers unfamiliar with healthspan studies using C. elegans and may help perform physiological experiments for healthy aging.
评估健康参数对于理解衰老过程中生理功能的衰退至关重要。线虫秀丽隐杆线虫是衰老研究中的一个强大模型。本文介绍了使用秀丽隐杆线虫评估健康参数的代表性方法，并提供了衰老过程中功能衰退的定量指标。这份手稿对于不熟悉使用秀丽隐杆线虫进行健康寿命研究的研究人员将有所帮助，并可能有助于开展健康衰老的生理学实验。
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