Luu Ngoc-Minh, Bui Thi-Tra, Phan Hai Thanh, Oh Jin-Kyung
School of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
Department of Cancer Control and Population Health, National Cancer Center Graduate School of Cancer Science and Policy, Goyang, Republic of Korea.
Asian Pac J Cancer Prev. 2025 Jun 1;26(6):2215-2223. doi: 10.31557/APJCP.2025.26.6.2215.
To examine the association between peer use and individual use of EC among adolescents and young adults.
We performed the search strategy on PubMed, EMBASE, and Cochrane. We selected prospective studies reporting adjusted odds ratio (aOR)/relative risk (aRR) with a 95% confidence interval (CI) and conducted a random-effects meta-analysis.
Eleven prospective studies were included, involving 32,014 participants in the quantitative analysis. Meta-analysis results showed a significant association between EC use by friends and increased odds of individual EC use (aOR = 1.79, 95% CI 1.43 to 2.25; I2 = 88.2% for ever use; aOR = 2.14, 95% CI 1.52 to 3.01; I2 = 88.5% for current use). In the subgroup meta-analysis of outcomes, having friends who used EC significantly increased the odds of ever- and current EC use. Similar findings were found in the subgroup meta-analyses by age group, region, sample size, study methodological quality, and follow-up time.
This study revealed a positive association between individual EC use and friends' use, especially among those under 18 years, suggesting targeting peer networks to curb the EC epidemic.
探讨青少年和青年中同伴使用紧急避孕药(EC)与个人使用之间的关联。
我们在PubMed、EMBASE和Cochrane上执行了检索策略。我们选择了报告经调整的优势比(aOR)/相对风险(aRR)及95%置信区间(CI)的前瞻性研究,并进行了随机效应荟萃分析。
纳入了11项前瞻性研究,定量分析涉及32,014名参与者。荟萃分析结果显示,朋友使用紧急避孕药与个人使用紧急避孕药的几率增加之间存在显著关联(曾经使用:aOR = 1.79,95% CI为1.43至2.25;I2 = 88.2%;当前使用:aOR = 2.14,95% CI为1.52至3.01;I2 = 88.5%)。在结局的亚组荟萃分析中,有使用紧急避孕药的朋友显著增加了曾经和当前使用紧急避孕药的几率。在按年龄组、地区、样本量、研究方法质量和随访时间进行的亚组荟萃分析中也发现了类似的结果。
本研究揭示了个人使用紧急避孕药与朋友使用之间存在正相关,尤其是在18岁以下人群中,这表明针对同伴网络来遏制紧急避孕药的流行。