Tang Yuyi, Ren Luo, Liu Enmei
Department of Respiratory Medicine Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Ministry of Education Key Laboratory of Child Development and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Key Laboratory of Pediatrics Chongqing China.
Pediatric Research Institute Children's Hospital of Chongqing Medical University Chongqing China.
Pediatr Discov. 2023 Oct 14;1(3):e33. doi: 10.1002/pdi3.33. eCollection 2023 Dec.
Respiratory tract infections (RTIs) are common and frequently occurring diseases in children, posing a significant health threat to children worldwide. Viruses are the most important pathogens of childhood RTIs. Since the outbreak of Coronavirus Disease 2019 (COVID-19), a series of nonpharmaceutical interventions (NPIs) have been widely implemented around the globe, and important changes have taken place in the spectrum of respiratory diseases and viruses in children. However, with relaxation of NPIs, there has been a "virus resurgence" in some areas, with multiple viral infectious diseases appearing simultaneously. This review comprehensively summarizes the changes observed in the spectrum of respiratory diseases and viruses in children in the context of the COVID-19 pandemic, explores possible mechanisms, and presents reflections on the key points of diagnosis and treatment of RTIs in children in the post-COVID-19 era in light of recent advances in COVID-19 in children.
呼吸道感染(RTIs)是儿童常见且频发的疾病,对全球儿童的健康构成重大威胁。病毒是儿童RTIs最重要的病原体。自2019年冠状病毒病(COVID-19)爆发以来,一系列非药物干预措施(NPIs)在全球范围内广泛实施,儿童呼吸道疾病和病毒谱发生了重要变化。然而,随着NPIs的放松,一些地区出现了“病毒复苏”,多种病毒传染病同时出现。本综述全面总结了在COVID-19大流行背景下儿童呼吸道疾病和病毒谱的变化,探讨了可能的机制,并根据儿童COVID-19的最新进展,对COVID-19后时代儿童RTIs的诊断和治疗要点进行了思考。