Lee Shin Hyung, Agley Jon, Sharma Vatsla, Williamson Francesca, Zhang Pengyue, Seo Dong-Chul
Department of Applied Health Science, Indiana University School of Public Health, Bloomington, Indiana, United States of America.
O'Neill School of Public and Environmental Affairs, Indiana University-Bloomington, Bloomington, Indiana, United States of America.
PLoS One. 2025 Jul 15;20(7):e0328444. doi: 10.1371/journal.pone.0328444. eCollection 2025.
Opioid overdose deaths pose a serious public health concern in the United States, with disproportionately higher rates of increase among Black Americans despite expanded naloxone access. Improving community knowledge and confidence in naloxone use may be critical to reducing these disparities.
This study assessed individual- and community-level factors associated with knowledge and perceived competency in managing opioid overdose and administering naloxone among urban Indiana residents.
A probability-based household survey was conducted between March to May 2023 across eight Indiana zip code areas (N = 772) with high (> 40%) proportions of Black residents. Multilevel modeling was used to examine individual- and community-level factors associated with opioid overdose knowledge and perceived competency, using adapted items from the Opioid Overdose Knowledge Scale (OOKS) and Opioid Overdose Attitudes Scale (OOAS).
Race, sex, household income, education, time lived in the community, and history of opioid overdose significantly predicted knowledge scores. White participants scored higher (mean 6.65) than Black participants (5.70) (p < 0.001). A significant cross-level interaction was found, with Black residents living in high-poverty areas scoring lower than White counterparts (β = 1.06, p = 0.039). In contrast, perceived competency was primarily associated with age and personal history of overdose.
Racial and socioeconomic disparities persist in opioid overdose knowledge, particularly among Black residents in low-income communities. Tailored, culturally responsive education efforts, especially by trusted community members, may help improve overdose response readiness.
阿片类药物过量致死在美国是一个严重的公共卫生问题,尽管纳洛酮的可及性有所提高,但美国黑人中的增长率却高得不成比例。提高社区对纳洛酮使用的认识和信心对于减少这些差异可能至关重要。
本研究评估了印第安纳州城市居民中与阿片类药物过量管理和纳洛酮给药知识及感知能力相关的个人和社区层面因素。
2023年3月至5月间,在印第安纳州八个邮政编码区域(N = 772)进行了一项基于概率的家庭调查,这些区域黑人居民比例较高(> 40%)。使用多水平模型,采用阿片类药物过量知识量表(OOKS)和阿片类药物过量态度量表(OOAS)中的改编项目,来检验与阿片类药物过量知识和感知能力相关的个人和社区层面因素。
种族、性别、家庭收入、教育程度、在社区居住的时间以及阿片类药物过量史显著预测了知识得分。白人参与者得分(平均6.65分)高于黑人参与者(5.70分)(p < 0.001)。发现了一个显著的跨层次交互作用,生活在高贫困地区的黑人居民得分低于白人居民(β = 1.06,p = 0.039)。相比之下,感知能力主要与年龄和个人过量用药史相关。
在阿片类药物过量知识方面,种族和社会经济差异依然存在,尤其是在低收入社区的黑人居民中。量身定制、具有文化适应性的教育努力,特别是由受信任的社区成员进行的教育,可能有助于提高应对过量用药的准备程度。