Ammar Mohammad, Russo Giovanni Luca, Altamimi Almothana, Altamimi Mohammad, Sabbah Mohammed, Al-Asmar Asmaa, Di Monaco Rossella
Department of Agricultural Sciences, Unit of Food Science and Technology, University of Naples Federico II, 80055 Portici, Italy.
Department of Medicine and Surgery, Università di Napoli Federico II, 80133 Naples, Italy.
Foods. 2025 Jul 16;14(14):2487. doi: 10.3390/foods14142487.
Breast milk is the optimal nutrition for infants, yet lactation insufficiency remains a common cause of early breastfeeding cessation. has been traditionally used as a galactagogue due to its rich micronutrient and phytosterol content. This systematic review assessed the effects of leaf supplementation on prolactin levels and breast milk volume in postpartum mothers with lactation insufficiency. A systematic search following PRISMA guidelines, was conducted for randomized controlled trials involving healthy postpartum women supplemented with . Risk of bias was evaluated using the Cochrane Risk of Bias Tool. Eight studies met the inclusion criteria, with intervention durations ranged from 3 to 10 days. supplementation increased significantly breast milk volume by up to 400 mL/day compared to controls. Serum prolactin levels also rose significantly with a mean increase of 231.72 ng/mL Most studies exhibited low to moderate risk of bias, though one study exhibited high risk due to lack of binding and subjective outcome measurement. leaf supplementation appears to enhance lactation by increasing milk volume and prolactin levels in postpartum mothers. However, further longer-term studies are needed to establish optimal dosing, sustained effectiveness, and safety.
母乳是婴儿的最佳营养来源,但泌乳不足仍是早期停止母乳喂养的常见原因。由于其富含微量营养素和植物甾醇,传统上一直被用作催乳剂。本系统评价评估了补充叶对泌乳不足的产后母亲催乳素水平和母乳量的影响。按照PRISMA指南进行系统检索,纳入涉及补充的健康产后妇女的随机对照试验。使用Cochrane偏倚风险工具评估偏倚风险。八项研究符合纳入标准,干预持续时间为3至10天。与对照组相比,补充显著增加了母乳量,每天增加多达400毫升。血清催乳素水平也显著升高,平均增加231.72纳克/毫升。大多数研究显示低至中度偏倚风险,尽管一项研究由于缺乏盲法和主观结局测量而显示高风险。补充叶似乎通过增加产后母亲的奶量和催乳素水平来促进泌乳。然而,需要进一步的长期研究来确定最佳剂量、持续有效性和安全性。