新型多烯衍生物鲁克诺霉素对念珠菌属和曲霉属的最小抑菌浓度
Minimal inhibitory concentrations of lucknomycin, a new polyenic derivative, for Candida and Aspergillus spp.
作者信息
Martínez-Quesada J, Torres-Rodriguez J M, Rosés-Codinachs M, Amaral-Olivera M
出版信息
Antimicrob Agents Chemother. 1983 Jul;24(1):132-3. doi: 10.1128/AAC.24.1.132.
Abstract
The minimal inhibitory concentrations (MICs) of lucknomycin, a new polyenic derivative, were determined for 101 clinical isolates of Candida, 38 clinical or environmental strains of Aspergillus fumigatus, and 30 isolates of A. niger. The most susceptible species were Candida albicans and Candida tropicalis (mean MIC, 0.4 micrograms/ml). Aspergillus spp. were less susceptible, with mean MICs of 0.60 micrograms/ml for Aspergillus niger and 9.2 micrograms/ml for Aspergillus fumigatus.
摘要
测定了新型多烯衍生物鲁克诺霉素对101株白色念珠菌临床分离株、38株烟曲霉临床或环境菌株以及30株黑曲霉分离株的最低抑菌浓度（MIC）。最敏感的菌种是白色念珠菌和热带念珠菌（平均MIC为0.4微克/毫升）。曲霉属菌株的敏感性较低，黑曲霉的平均MIC为0.60微克/毫升，烟曲霉的平均MIC为9.2微克/毫升。
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