白色念珠菌对两性霉素B和两性霉素B甲酯的敏感性比较。
Comparative susceptibility of Candida albicans to amphotericin B and amphotericin B methyl ester.
作者信息
Bannatyne R M, Cheung R
出版信息
Antimicrob Agents Chemother. 1977 Oct;12(4):449-50. doi: 10.1128/AAC.12.4.449.
Abstract
The in vitro antifungal activities of amphotericin B (AMB) and amphotericin B methyl ester (AME) were compared against 465 clinical isolates of Candida albicans. AMB and AME possessed comparable activity against half of the strains, but against the remainder of the strains the activity of AME was slightly lower than that of AMB. Rarely did AME show superior antifungal activity to AMB.
摘要
比较了两性霉素B（AMB）和两性霉素B甲酯（AME）对465株白色念珠菌临床分离株的体外抗真菌活性。AMB和AME对一半的菌株具有相当的活性，但对其余菌株，AME的活性略低于AMB。AME很少表现出比AMB更强的抗真菌活性。
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