伴侣蛋白DnaK和GroEL在细菌包涵体中的定位。
Localization of chaperones DnaK and GroEL in bacterial inclusion bodies.
作者信息
Carrió M Mar, Villaverde Antonio
机构信息
Institut de Biotecnologia i de Biomedicina and Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain
出版信息
J Bacteriol. 2005 May;187(10):3599-601. doi: 10.1128/JB.187.10.3599-3601.2005.
Abstract
By immunostaining and transmission electron microscopy, chaperones DnaK and GroEL have been identified at the solvent-exposed surface of bacterial inclusion bodies and entrapped within these aggregates, respectively. Functional implications of this distinct localization are discussed in the context of Escherichia coli protein quality control.
摘要
通过免疫染色和透射电子显微镜观察，伴侣蛋白DnaK和GroEL已分别在细菌包涵体暴露于溶剂的表面以及被困在这些聚集体中被鉴定出来。在大肠杆菌蛋白质质量控制的背景下讨论了这种独特定位的功能意义。
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