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对腹泻患者粪便微生物群的监测表明其组成存在畸变。

Monitoring of stool microbiota in subjects with diarrhea indicates distortions in composition.

作者信息

Mai Volker, Braden Christopher R, Heckendorf Jill, Pironis Baiba, Hirshon Jon Mark

机构信息

Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Rm. 934-B MSTF, 10 S. Pine St., Baltimore, MD 21201, USA.

出版信息

J Clin Microbiol. 2006 Dec;44(12):4550-2. doi: 10.1128/JCM.01542-06. Epub 2006 Oct 4.

Abstract

We utilized denaturing gradient gel electrophoresis profiling to survey stool microbiota in 175 persons with diarrhea and 113 asymptomatic persons in a diarrhea surveillance study. Compared with healthy controls, the microbiota profiles in diarrhea cases more frequently exhibited decreased diversity and strong bands indicating the overgrowth of selected bacteria or bacterial groups.

摘要

在一项腹泻监测研究中,我们利用变性梯度凝胶电泳分析技术,对175名腹泻患者和113名无症状者的粪便微生物群进行了调查。与健康对照组相比,腹泻病例的微生物群谱更频繁地表现出多样性降低以及表明特定细菌或细菌群过度生长的强条带。

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