用于 Fe³⁺生物成像的高选择性荧光化学传感器。
A highly selective, fluorescent chemosensor for bioimaging of Fe³⁺.
机构信息
State Key Laboratory of Fine Chemicals, Dalian University of Technology, 2 Linggong Rd., Hi-tech Zone, Dalian 116024, PR China.
出版信息
Bioorg Med Chem Lett. 2011 Sep 15;21(18):5413-6. doi: 10.1016/j.bmcl.2011.07.001. Epub 2011 Jul 13.
PMID:21802288
Abstract
A fluorescent sensor for Fe(3+) has been synthesized based on rhodamine-lactam, which shows excitation (531 nm) and emission (557 nm) wavelength, displays an excellent selectivity for Fe(3+) and can be used for imaging Fe(3+) in living cells. The pK(a) of the sensor is as low as of 3.2. It can be used in the range of pH 5-9.
摘要
一种基于洛派丁胺的荧光传感器已被合成用于检测 Fe(3+)，该传感器具有激发（531nm）和发射（557nm）波长，对 Fe(3+) 具有优异的选择性，可用于活细胞中 Fe(3+)的成像。该传感器的 pK(a) 值低至 3.2。它可以在 pH 值 5-9 的范围内使用。
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