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恢复性生物过程与健康。

Restorative biological processes and health.

作者信息

Robles Theodore F, Carroll Judith E

机构信息

Department of Psychology, University of California, Los Angeles.

出版信息

Soc Personal Psychol Compass. 2011 Aug;5(8):518-537. doi: 10.1111/j.1751-9004.2011.00368.x.

Abstract

Research on psychological influences on physiology primarily focuses on biological responses during stressful challenges, and how those responses can become dysregulated with prolonged or repeated exposure to stressful circumstances. At the same time, humans spend considerable time recovering from those challenges, and a host of biological processes involved in restoration and repair take place during normal, non-stressed activities. We review restorative biological processes and evidence for links between psychosocial factors and several restorative processes including sleep, wound healing, antioxidant production, DNA repair, and telomerase function. Across these biological processes, a growing body of evidence suggests that experiencing negative emotional states, including acute and chronic stress, depressive symptoms, and individual differences in negative affectivity and hostility, can influence these restorative processes. This review calls attention to restorative processes as fruitful mechanisms and outcomes for future biobehavioral research.

摘要

关于心理对生理影响的研究主要聚焦于应激挑战期间的生物反应,以及长时间或反复暴露于应激环境时这些反应如何失调。与此同时,人类会花费大量时间从这些挑战中恢复,在正常的非应激活动中会发生一系列参与恢复和修复的生物过程。我们综述了恢复性生物过程以及社会心理因素与包括睡眠、伤口愈合、抗氧化剂产生、DNA修复和端粒酶功能在内的几种恢复过程之间联系的证据。在这些生物过程中,越来越多的证据表明,经历负面情绪状态,包括急性和慢性应激、抑郁症状以及消极情感和敌意方面的个体差异,会影响这些恢复过程。本综述提请人们注意恢复过程,将其作为未来生物行为研究富有成效的机制和成果。

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