2010 年至 2013 年沙特阿拉伯国内牲畜中东呼吸综合征（MERS）冠状病毒血清流行率。
Middle East Respiratory Syndrome (MERS) coronavirus seroprevalence in domestic livestock in Saudi Arabia, 2010 to 2013.
机构信息
These authors contributed equally to this work.
出版信息
Euro Surveill. 2013 Dec 12;18(50):20659. doi: 10.2807/1560-7917.es2013.18.50.20659.
In Saudi Arabia, including regions of Riyadh and Al Ahsa, pseudoparticle neutralisation (ppNT) and microneutralisation (MNT) tests detected no antibodies to Middle East Respiratory Syndrome coronavirus (MERS-CoV) in sheep (n= 100), goats (n= 45), cattle (n= 50) and chickens (n= 240). Dromedary camels however, had a high prevalence of MERS-CoV antibodies. Bovine coronavirus (BCoV) infected sera from cattle had no cross-reactivity in MERS-CoV ppNT or MNT, while many dromedary camels’ sera reacted to both BCoV and MERS-CoV. Some nevertheless displayed specific serologic reaction profiles to MERS-CoV.
在沙特阿拉伯，包括利雅得和艾卜哈地区在内，进行的假病毒中和（ppNT）和微量中和（MNT）检测并未在绵羊（n=100）、山羊（n=45）、牛（n=50）和鸡（n=240）中检测到中东呼吸综合征冠状病毒（MERS-CoV）抗体。然而，单峰骆驼的 MERS-CoV 抗体阳性率很高。牛冠状病毒（BCoV）感染牛血清在 MERS-CoV ppNT 或 MNT 中无交叉反应，而许多单峰骆驼血清既与 BCoV 又与 MERS-CoV 反应。然而，有些血清仍表现出针对 MERS-CoV 的特异性血清学反应谱。
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