一种用于检测活细胞中生物源性二氧化硫衍生物的线粒体靶向比色和比率荧光探针。
A mitochondria-targeted colorimetric and ratiometric fluorescent probe for biological SO2 derivatives in living cells.
作者信息
Liu Yu, Li Kun, Wu Ming-Yu, Liu Yan-Hong, Xie Yong-Mei, Yu Xiao-Qi
机构信息
Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry Sichuan University, 29, Wangjiang Road, Chengdu, Sichuan Province, China.
出版信息
Chem Commun (Camb). 2015 Jun 25;51(50):10236-9. doi: 10.1039/c5cc03055b. Epub 2015 May 29.
PMID:26021301
Abstract
A ratiometric fluorescent probe for SO2 derivatives based on the conjugate of carbazole and indolium was presented, which could selectively respond to HSO3(-) over other thiol compounds. More importantly, CZ-Id is a novel mitochondria-targeted ratiometric fluorescent probe to image exogenous SO2 derivatives.
摘要
报道了一种基于咔唑与吲哚鎓共轭物的用于二氧化硫衍生物的比率荧光探针，该探针能够比其他硫醇化合物更具选择性地响应亚硫酸氢根离子。更重要的是，CZ-Id是一种新型的线粒体靶向比率荧光探针，用于对外源性二氧化硫衍生物进行成像。
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