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食品中病毒污染的流行情况及评估策略:对人类健康的风险——综述

Prevalence and evaluation strategies for viral contamination in food products: Risk to human health-a review.

机构信息

a Department of Food Science and Technology , Yeungnam University , Gyeongsan-si , Gyeongsangbuk-do , Republic of Korea.

b Department of Energy and Materials Engineering , Dongguk University , Seoul , Republic of Korea.

出版信息

Crit Rev Food Sci Nutr. 2018 Feb 11;58(3):405-419. doi: 10.1080/10408398.2016.1182891. Epub 2017 Jun 28.

Abstract

Nowadays, viruses of foodborne origin such as norovirus and hepatitis A are considered major causes of foodborne gastrointestinal illness with widespread distribution worldwide. A number of foodborne outbreaks associated with food products of animal and non-animal origins, which often involve multiple cases of variety of food streams, have been reported. Although several viruses, including rotavirus, adenovirus, astrovirus, parvovirus, and other enteroviruses, significantly contribute to incidence of gastrointestinal diseases, systematic information on the role of food in transmitting such viruses is limited. Most of the outbreak cases caused by infected food handlers were the source of 53% of total outbreaks. Therefore, prevention and hygiene measures to reduce the frequency of foodborne virus outbreaks should focus on food workers and production site of food products. Pivotal strategies, such as proper investigation, surveillance, and reports on foodborne viral illnesses, are needed in order to develop more accurate measures to detect the presence and pathogenesis of viral infection with detailed descriptions. Moreover, molecular epidemiology and surveillance of food samples may help analysis of public health hazards associated with exposure to foodborne viruses. In this present review, we discuss different aspects of foodborne viral contamination and its impact on human health. This review also aims to improve understanding of foodborne viral infections as major causes of human illness as well as provide descriptions of their control and prevention strategies and rapid detection by advanced molecular techniques. Further, a brief description of methods available for the detection of viruses in food and related matrices is provided.

摘要

如今,食源病毒(如诺如病毒和甲型肝炎病毒)被认为是全球范围内广泛分布的食源性胃肠道疾病的主要原因。已经报道了许多与动物和非动物来源的食品有关的食源性暴发事件,这些事件通常涉及多种食品流的多种病例。虽然包括轮状病毒、腺病毒、星状病毒、细小病毒和其他肠道病毒在内的几种病毒对胃肠道疾病的发病率有重大影响,但有关食源性传播此类病毒作用的系统信息有限。大多数由受感染的食品处理人员引起的暴发病例是总暴发的 53%的来源。因此,预防和卫生措施应侧重于减少食源病毒暴发的频率食品工人和食品产品的生产地点。为了制定更准确的措施来检测病毒感染的存在和发病机制,并详细描述,需要采取适当的调查、监测和报告食源性病毒病等关键策略。此外,对食品样本的分子流行病学和监测可能有助于分析与接触食源病毒相关的公共卫生危害。在本次综述中,我们讨论了食源病毒污染的不同方面及其对人类健康的影响。本综述还旨在提高对食源病毒感染作为人类疾病主要原因的理解,并提供有关其控制和预防策略以及通过先进分子技术快速检测的描述。此外,还简要描述了用于检测食品和相关基质中病毒的方法。

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