Gazal Giath, Fareed Wamiq Musheer, Zafar Muhammad Sohail, Al-Samadani Khalid H
Department of Oral and Maxillofacial Surgery, College of Dentistry, Taibah University, P.O. Box 2898, Al Madinah Al Munawwarah, Saudi Arabia.
Department of Restorative Dentistry, College of Dentistry, Taibah University, P.O. Box 2898, Al Madinah Al Munawwarah, Saudi Arabia.
Saudi Pharm J. 2016 Jul;24(4):379-85. doi: 10.1016/j.jsps.2014.04.004. Epub 2014 Apr 26.
For fearful and uncooperative children behavioral management techniques are used. In order to control the pain and anxiety in pedodontic patients, pharmacologic sedation, anesthesia and analgesia are commonly used. Midazolam is commonly used as an oral sedation agent in children; it has several features such as safety of use, quick onset and certain degree of amnesia that makes it a desirable sedation agent in children. This review paper discusses various aspects of oral midazolam, ketamine and their combinations in conscious sedation including, advantages of oral route of sedation, pharmacokinetics, range of oral doses, and antagonists for clinical dental treatment procedures.
对于恐惧和不合作的儿童,会采用行为管理技术。为了控制儿童牙科患者的疼痛和焦虑,通常会使用药物镇静、麻醉和镇痛方法。咪达唑仑常用于儿童口服镇静;它具有使用安全、起效快和一定程度的遗忘等特点,使其成为儿童理想的镇静剂。这篇综述文章讨论了口服咪达唑仑、氯胺酮及其组合在清醒镇静中的各个方面,包括口服镇静途径的优势、药代动力学、口服剂量范围以及用于临床牙科治疗程序的拮抗剂。