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蝙蝠作为病毒的储存库。

Bats as Viral Reservoirs.

机构信息

Molecular Epidemiology and Public Health Laboratory, Infectious Disease Research Centre, Hopkirk Research Institute, Massey University, Palmerston North 4442, New Zealand; email:

出版信息

Annu Rev Virol. 2016 Sep 29;3(1):77-99. doi: 10.1146/annurev-virology-110615-042203. Epub 2016 Aug 22.

Abstract

Bats are hosts of a range of viruses, including ebolaviruses, and many important human viral infections, such as measles and mumps, may have their ancestry traced back to bats. Here, I review viruses of all viral families detected in global bat populations. The viral diversity in bats is substantial, and viruses with all known types of genomic structures and replication strategies have been discovered in bats. However, the discovery of viruses is not geographically even, with some apparently undersampled regions, such as South America. Furthermore, some bat families, including those with global or wide distributions such as Emballonuridae and Miniopteridae, are underrepresented on viral databases. Future studies, including those that address these sampling gaps along with those that develop our understanding of viral-host relationships, are highlighted.

摘要

蝙蝠是一系列病毒的宿主,包括埃博拉病毒,而麻疹和腮腺炎等许多重要的人类病毒性传染病可能都可以追溯到蝙蝠身上。在这里,我综述了在全球蝙蝠种群中检测到的所有病毒科的病毒。蝙蝠所携带的病毒多样性非常丰富,已经发现了具有所有已知基因组结构和复制策略的病毒。然而,病毒的发现并不是在地理上均匀的,有些地区显然采样不足,例如南美洲。此外,一些蝙蝠科,包括那些具有全球性或广泛分布的科,如 Emballonuridae 和 Miniopteridae,在病毒数据库中的代表性不足。未来的研究,包括解决这些采样差距的研究,以及那些有助于我们理解病毒与宿主关系的研究,都被强调了。

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