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哪些临床和患者因素会影响全关节置换术后再入院的国家经济负担?

Which Clinical and Patient Factors Influence the National Economic Burden of Hospital Readmissions After Total Joint Arthroplasty?

作者信息

Kurtz Steven M, Lau Edmund C, Ong Kevin L, Adler Edward M, Kolisek Frank R, Manley Michael T

机构信息

Exponent Inc, 3440 Market Street, Suite 600, Philadelphia, PA, 19104, USA.

School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA.

出版信息

Clin Orthop Relat Res. 2017 Dec;475(12):2926-2937. doi: 10.1007/s11999-017-5244-6.

Abstract

BACKGROUND

The Affordable Care Act of 2010 advanced the economic model of bundled payments for total joint arthroplasty (TJA), in which hospitals will be financially responsible for readmissions, typically at 90 days after surgery. However, little is known about the financial burden of readmissions and what patient, clinical, and hospital factors drive readmission costs.

QUESTIONS/PURPOSES: (1) What is the incidence, payer mix, and demographics of THA and TKA readmissions in the United States? (2) What patient, clinical, and hospital factors are associated with the cost of 30- and 90-day readmissions after primary THA and TKA? (3) Are there any differences in the economic burden of THA and TKA readmissions between payers? (4) What types of THA and TKA readmissions are most costly to the US hospital system?

METHODS

The recently developed Nationwide Readmissions Database from the Healthcare Cost and Utilization Project (2006 hospitals from 21 states) was used to identify 719,394 primary TJAs and 62,493 90-day readmissions in the first 9 months of 2013 based on International Classification of Diseases, 9th Revision, Clinical Modification codes. We classified the reasons for readmissions as either procedure- or medical-related. Cost-to-charge ratios supplied with the Nationwide Readmissions Database were used to compute the individual per-patient cost of 90-day readmissions as a continuous variable in separate general linear models for THA and TKA. Payer, patient, clinical, and hospital factors were treated as covariates. We estimated the national burden of readmissions by payer and by the reason for readmission.

RESULTS

The national rates of 30- and 90-day readmissions after THA were 4% (95% confidence interval [CI], 4.2%-4.5%) and 8% (95% CI, 7.5%-8.1%), respectively. The national rates of 30- and 90-day readmissions after primary TKA were 4% (95% CI, 3.8%-4.0%) and 7% (95% CI, 6.8%-7.2%), respectively. The five most important variables responsible for the cost of 90-day THA readmissions (in rank order, based on the Type III F-statistic, p < 0.001) were length of stay (LOS), all patient-refined diagnosis-related group (APR DRG) severity, type of readmission (that is, medical- versus procedure-related), hospital ownership, and age. Likewise, the five most important variables responsible for the cost of 90-day TKA readmissions were LOS, APR DRG severity, gender, hospital procedure volume, and hospital ownership. After adjusting for covariates, mean 90-day readmission costs reimbursed by private insurance were, on average, USD 1324 and USD 1372 greater than Medicare (p < 0.001) for THA and TKA, respectively. In the 90 days after TJA, two-thirds of the total annual readmission costs were covered by Medicare. In 90 days after THA, more readmissions were still associated with procedure-related complications, including infections, dislocations, and periprosthetic fractures, which in aggregate account for 59% (95% CI, 59.1%-59.6%) of the total readmission costs to the US healthcare system. For TKA, 49% of the total readmission cost (95% CI, 48.8%-49.6%) in 90 days for the United States was associated with procedure issues, most notably including infections.

CONCLUSIONS

Hospital readmissions up to 90 days after TJA represent a massive economic burden on the US healthcare system. Approximately half of the total annual economic burden for readmissions in the United States is medical and unrelated to the joint replacement procedure and half is related to procedural complications.

CLINICAL RELEVANCE

This national study underscores LOS during readmission as a primary cost driver, suggesting that hospitals and doctors further optimize, to the extent possible, the clinical pathways for the hospitalization of readmitted patients. Because patients readmitted as a result of infection, dislocation, and periprosthetic fractures are the most costly types of readmissions, efforts to reduce the LOS for these types of readmissions will have the greatest impact on their economic burden. Additional clinical research is needed to determine the extent to which, if any, the LOS during readmissions can be reduced without sacrificing quality or access of care.

摘要

背景

2010年的《平价医疗法案》推进了全关节置换术(TJA)捆绑支付的经济模式,在此模式下,医院将对再入院治疗承担经济责任,通常是在术后90天。然而,对于再入院治疗的经济负担以及促使再入院费用产生的患者、临床和医院因素,我们知之甚少。

问题/目的:(1)美国全髋关节置换术(THA)和全膝关节置换术(TKA)再入院治疗的发生率、支付方构成及人口统计学特征是什么?(2)初次THA和TKA术后30天及90天再入院治疗费用与哪些患者、临床和医院因素相关?(3)不同支付方之间,THA和TKA再入院治疗的经济负担有无差异?(4)对美国医院系统而言,哪些类型的THA和TKA再入院治疗成本最高?

方法

利用医疗成本与利用项目最新开发的全国再入院数据库(来自21个州的2006家医院),根据国际疾病分类第九版临床修订本编码,识别出2013年前9个月的719,394例初次TJA病例及62,493例90天内再入院病例。我们将再入院原因分为与手术相关或与医疗相关两类。利用全国再入院数据库提供的成本收费比,在针对THA和TKA的单独一般线性模型中,将90天再入院治疗的每位患者个体成本作为连续变量进行计算。支付方、患者、临床和医院因素作为协变量处理。我们按支付方和再入院原因估算了全国再入院治疗的负担。

结果

THA术后30天和90天的全国再入院率分别为4%(95%置信区间[CI],4.2% - 4.5%)和8%(95%CI,7.5% - 8.1%)。初次TKA术后30天和90天的全国再入院率分别为4%(95%CI,3.8% - 4.0%)和7%(95%CI,6.8% - 7.2%)。导致90天THA再入院治疗费用的五个最重要变量(按III型F统计量排序,p < 0.001)依次为住院时间(LOS)、所有患者细化诊断相关分组(APR DRG)严重程度、再入院类型(即与医疗相关还是与手术相关)、医院所有权性质和年龄。同样,导致90天TKA再入院治疗费用的五个最重要变量为住院时间、APR DRG严重程度、性别、医院手术量和医院所有权性质。在对协变量进行调整后,私人保险报销的90天再入院平均费用,THA比医疗保险平均高出1324美元,TKA比医疗保险平均高出1372美元(p < 0.001)。在TJA术后90天内,年度再入院治疗总费用的三分之二由医疗保险支付。在THA术后90天内,更多再入院治疗仍与手术相关并发症有关,包括感染、脱位和假体周围骨折,这些并发症总计占美国医疗系统再入院治疗总费用的59%(95%CI,59.1% - 59.6%)。对于TKA,美国90天内再入院治疗总费用的49%(95%CI,48.8% - 49.6%)与手术问题相关,最主要的是感染。

结论

TJA术后90天内的医院再入院治疗给美国医疗系统带来了巨大的经济负担。美国再入院治疗年度经济负担中约一半是医疗性的且与关节置换手术无关,另一半与手术并发症相关。

临床意义

这项全国性研究强调再入院期间的住院时间是主要的成本驱动因素,这表明医院和医生应尽可能进一步优化再入院患者的住院临床路径。由于因感染、脱位和假体周围骨折而再次入院的患者是成本最高的再入院类型,努力缩短这些类型再入院的住院时间将对其经济负担产生最大影响。还需要进行更多临床研究,以确定在不牺牲医疗质量或可及性的前提下,再入院期间的住院时间能够缩短的程度。

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