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国际核苷酸序列数据库合作组织。

The international nucleotide sequence database collaboration.

机构信息

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

DDBJ Center, National Institute for Genetics, Mishima, Japan.

出版信息

Nucleic Acids Res. 2018 Jan 4;46(D1):D48-D51. doi: 10.1093/nar/gkx1097.

Abstract

For more than 30 years, the International Nucleotide Sequence Database Collaboration (INSDC; http://www.insdc.org/) has been committed to capturing, preserving and providing access to comprehensive public domain nucleotide sequence and associated metadata which enables discovery in biomedicine, biodiversity and biological sciences. Since 1987, the DNA Data Bank of Japan (DDBJ) at the National Institute for Genetics in Mishima, Japan; the European Nucleotide Archive (ENA) at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK; and GenBank at National Center for Biotechnology Information (NCBI), National Library of Medicine, National Institutes of Health in Bethesda, Maryland, USA have worked collaboratively to enable access to nucleotide sequence data in standardized formats for the worldwide scientific community. In this article, we reiterate the principles of the INSDC collaboration and briefly summarize the trends of the archival content.

摘要

三十多年来,国际核苷酸序列数据库合作组织(INSDC;http://www.insdc.org/)一直致力于捕获、保存和提供全面的公共领域核苷酸序列及相关元数据,这些数据使生物医学、生物多样性和生命科学领域的发现成为可能。自 1987 年以来,日本国立遗传学研究所的 DNA 数据库(DDBJ)、英国欧洲分子生物学实验室欧洲生物信息学研究所(EMBL-EBI)的欧洲核苷酸档案馆(ENA)和美国马里兰州贝塞斯达市国立生物技术信息中心(NCBI)的国家医学图书馆的 GenBank 一直合作,以实现标准化格式的核苷酸序列数据向全球科学界开放。本文中,我们重申了 INSDC 合作的原则,并简要总结了归档内容的发展趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f953/5753279/629a996338e7/gkx1097fig1.jpg

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