Virgili Gianni, Acosta Ruthy, Bentley Sharon A, Giacomelli Giovanni, Allcock Claire, Evans Jennifer R
Department of Translational Surgery and Medicine, Eye Clinic, University of Florence, Largo Brambilla, 3, Florence, Italy, 50134.
Cochrane Database Syst Rev. 2018 Apr 17;4(4):CD003303. doi: 10.1002/14651858.CD003303.pub4.
The purpose of low-vision rehabilitation is to allow people to resume or to continue to perform daily living tasks, with reading being one of the most important. This is achieved by providing appropriate optical devices and special training in the use of residual-vision and low-vision aids, which range from simple optical magnifiers to high-magnification video magnifiers.
To assess the effects of different visual reading aids for adults with low vision.
We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (which contains the Cochrane Eyes and Vision Trials Register) (2017, Issue 12); MEDLINE Ovid; Embase Ovid; BIREME LILACS, OpenGrey, the ISRCTN registry; ClinicalTrials.gov and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP). The date of the search was 17 January 2018.
This review includes randomised and quasi-randomised trials that compared any device or aid used for reading to another device or aid in people aged 16 or over with low vision as defined by the study investigators. We did not compare low-vision aids with no low-vision aid since it is obviously not possible to measure reading speed, our primary outcome, in people that cannot read ordinary print. We considered reading aids that maximise the person's visual reading capacity, for example by increasing image magnification (optical and electronic magnifiers), augmenting text contrast (coloured filters) or trying to optimise the viewing angle or gaze position (such as prisms). We have not included studies investigating reading aids that allow reading through hearing, such as talking books or screen readers, or through touch, such as Braille-based devices and we did not consider rehabilitation strategies or complex low-vision interventions.
We used standard methods expected by Cochrane. At least two authors independently assessed trial quality and extracted data. The primary outcome of the review was reading speed in words per minute. Secondary outcomes included reading duration and acuity, ease and frequency of use, quality of life and adverse outcomes. We graded the certainty of the evidence using GRADE.
We included 11 small studies with a cross-over design (435 people overall), one study with two parallel arms (37 participants) and one study with three parallel arms (243 participants). These studies took place in the USA (7 studies), the UK (5 studies) and Canada (1 study). Age-related macular degeneration (AMD) was the most frequent cause of low vision, with 10 studies reporting 50% or more participants with the condition. Participants were aged 9 to 97 years in these studies, but most were older (the median average age across studies was 71 years). None of the studies were masked; otherwise we largely judged the studies to be at low risk of bias. All studies reported the primary outcome: results for reading speed. None of the studies measured or reported adverse outcomes.Reading speed may be higher with stand-mounted closed circuit television (CCTV) than with optical devices (stand or hand magnifiers) (low-certainty evidence, 2 studies, 92 participants). There was moderate-certainty evidence that reading duration was longer with the electronic devices and that they were easier to use. Similar results were seen for electronic devices with the camera mounted in a 'mouse'. Mixed results were seen for head-mounted devices with one study of 70 participants finding a mouse-based head-mounted device to be better than an optical device and another study of 20 participants finding optical devices better (low-certainty evidence). Low-certainty evidence from three studies (93 participants) suggested no important differences in reading speed, acuity or ease of use between stand-mounted and head-mounted electronic devices. Similarly, low-certainty evidence from one study of 100 participants suggested no important differences between a 9.7'' tablet computer and stand-mounted CCTV in reading speed, with imprecise estimates (other outcomes not reported).Low-certainty evidence showed little difference in reading speed in one study with 100 participants that added electronic portable devices to preferred optical devices. One parallel-arm study in 37 participants found low-certainty evidence of higher reading speed at one month if participants received a CCTV at the initial rehabilitation consultation instead of a standard low-vision aids prescription alone.A parallel-arm study including 243 participants with AMD found no important differences in reading speed, reading acuity and quality of life between prism spectacles and conventional spectacles. One study in 10 people with AMD found that reading speed with several overlay coloured filters was no better and possibly worse than with a clear filter (low-certainty evidence, other outcomes not reported).
AUTHORS' CONCLUSIONS: There is insufficient evidence supporting the use of a specific type of electronic or optical device for the most common profiles of low-vision aid users. However, there is some evidence that stand-mounted electronic devices may improve reading speeds compared with optical devices. There is less evidence to support the use of head-mounted or portable electronic devices; however, the technology of electronic devices may have improved since the studies included in this review took place, and modern portable electronic devices have desirable properties such as flexible use of magnification. There is no good evidence to support the use of filters or prism spectacles. Future research should focus on assessing sustained long-term use of each device and the effect of different training programmes on its use, combined with investigation of which patient characteristics predict performance with different devices, including some of the more costly electronic devices.
低视力康复的目的是让人们能够恢复或继续进行日常生活活动,其中阅读是最重要的活动之一。这通过提供合适的光学设备以及针对残余视力和低视力辅助器具使用的特殊训练来实现,这些辅助器具范围从简单的光学放大镜到高倍视频放大镜。
评估不同视觉阅读辅助器具对成年低视力患者的效果。
我们检索了Cochrane对照试验中心注册库(CENTRAL)(其中包含Cochrane眼科和视力试验注册库)(2017年第12期);MEDLINE(Ovid平台);Embase(Ovid平台);拉丁美洲及加勒比地区健康科学文献数据库(BIREME LILACS)、OpenGrey、国际标准随机对照试验编号注册库(ISRCTN registry);美国国立医学图书馆临床试验注册库(ClinicalTrials.gov)以及世界卫生组织(WHO)国际临床试验注册平台(ICTRP)。检索日期为2018年1月17日。
本综述纳入了随机和半随机试验,这些试验比较了16岁及以上低视力患者(由研究调查人员定义)用于阅读的任何一种设备或辅助器具与另一种设备或辅助器具。我们没有将低视力辅助器具与无低视力辅助器具进行比较,因为显然无法测量不能阅读普通印刷品的人的阅读速度,而阅读速度是我们的主要结局指标。我们考虑的阅读辅助器具是那些能最大化个人视觉阅读能力的器具,例如通过增加图像放大倍数(光学和电子放大镜)、增强文本对比度(彩色滤光片)或尝试优化视角或注视位置(如棱镜)。我们未纳入研究通过听觉(如有声读物或屏幕阅读器)或触觉(如基于盲文的设备)进行阅读的辅助器具的研究,并且我们没有考虑康复策略或复杂的低视力干预措施。
我们采用了Cochrane期望的标准方法。至少两名作者独立评估试验质量并提取数据。本综述的主要结局指标是每分钟的阅读速度。次要结局指标包括阅读时长和视力、使用的难易程度和频率、生活质量以及不良结局。我们使用GRADE方法对证据的确定性进行分级。
我们纳入了11项采用交叉设计的小型研究(共435人)、1项有两个平行组的研究(37名参与者)以及1项有三个平行组的研究(243名参与者)。这些研究在美国进行了7项、英国5项、加拿大1项。年龄相关性黄斑变性(AMD)是低视力最常见的病因,10项研究报告称50%或更多的参与者患有该疾病。这些研究中的参与者年龄在9至97岁之间,但大多数年龄较大(各研究的年龄中位数为71岁)。所有研究均未采用盲法;除此之外,我们在很大程度上判断这些研究的偏倚风险较低。所有研究均报告了主要结局指标:阅读速度的结果。没有研究测量或报告不良结局。站立式闭路电视(CCTV)的阅读速度可能高于光学设备(站立式或手持式放大镜)(低确定性证据,2项研究,92名参与者)。有中等确定性证据表明,电子设备的阅读时长更长且使用更方便。对于摄像头安装在“鼠标”中的电子设备也观察到了类似结果。对于头戴式设备,结果不一,一项有70名参与者的研究发现基于鼠标的头戴式设备优于光学设备,而另一项有20名参与者的研究发现光学设备更好(低确定性证据)。三项研究(93名参与者)的低确定性证据表明,站立式和头戴式电子设备在阅读速度、视力或使用便利性方面没有重要差异。同样,一项有100名参与者的研究的低确定性证据表明,9.7英寸平板电脑和站立式CCTV在阅读速度方面没有重要差异,但估计值不精确(未报告其他结局)。一项有100名参与者的研究的低确定性证据表明,在首选光学设备的基础上增加电子便携式设备,阅读速度几乎没有差异。一项有37名参与者的平行组研究发现,低确定性证据表明,如果参与者在初始康复咨询时接受CCTV而不是仅开具标准的低视力辅助器具处方,一个月时阅读速度更高。一项纳入243名AMD患者的平行组研究发现,棱镜眼镜和传统眼镜在阅读速度、阅读视力和生活质量方面没有重要差异。一项有10名AMD患者的研究发现,使用几种叠加彩色滤光片的阅读速度不比使用透明滤光片好,甚至可能更差(低确定性证据,未报告其他结局)。
对于低视力辅助器具使用者的最常见类型,没有足够的证据支持使用特定类型的电子或光学设备。然而,有一些证据表明,与光学设备相比,站立式电子设备可能会提高阅读速度。支持使用头戴式或便携式电子设备的证据较少;然而,自本综述纳入的研究开展以来,电子设备技术可能已经有所改进,现代便携式电子设备具有如灵活使用放大功能等理想特性。没有充分的证据支持使用滤光片或棱镜眼镜。未来的研究应侧重于评估每种设备的长期持续使用情况以及不同训练方案对其使用的影响,同时结合调查哪些患者特征可预测使用不同设备(包括一些更昂贵的电子设备)的表现。