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经皮肤吸收所致系统性中毒性百草枯中毒的成功治疗:病例报告及文献综述

The successful treatment of systemic toxic induced paraquat poisoning by skin absorption: case reports and a literature review.

作者信息

Wang Jia-Wei, Yang Xia, Ning Bin-Yuan, Yang Ze-Yu, Luo Li-Hui, Xiao Huan, Ning Zong

机构信息

Department of Emergency, The First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China.

出版信息

Int J Clin Exp Pathol. 2019 Sep 1;12(9):3662-3670. eCollection 2019.

Abstract

Paraquat (PQ) poisoning is life-threatening, can cause acute organ damage, and has a high mortality. However, cases of skin absorption induced by PQ poisoning are rare. This report describes a case where PQ was absorbed by the patient's skin, causing severe organ damage. Having accidentally touched PQ on his skin, the patient, whose skin festered, became damaged, red, and swollen, developed serious systemic toxic symptoms. The patient recovered after systemic treatment. Generally speaking, being poisoned by PQ through skin absorption is rare. By analyzing the reported PQ poisoning through skin absorption and by reviewing the relevant literature, this paper aims to explore successful treatments for PQ poisoning through skin absorption and to provide treatment guidance for physicians encountering such cases.

摘要

百草枯(PQ)中毒危及生命,可导致急性器官损伤,死亡率很高。然而,由PQ中毒引起的皮肤吸收病例很少见。本报告描述了一例PQ经患者皮肤吸收,导致严重器官损伤的病例。患者皮肤意外接触到PQ后,皮肤溃烂、破损、红肿,并出现严重的全身中毒症状。经全身治疗后患者康复。一般来说,通过皮肤吸收导致PQ中毒的情况很少见。通过分析已报道的经皮肤吸收的PQ中毒病例并查阅相关文献,本文旨在探索经皮肤吸收的PQ中毒的成功治疗方法,并为遇到此类病例的医生提供治疗指导。

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