接触低浓度氨导致的呼吸障碍：一项为期 5 年的历史队列研究。
Respiratory Disorders Resulting From Exposure to Low Concentrations of Ammonia: A 5-Year Historical Cohort Study.
机构信息
Department of Occupational Safety & Health Engineering, Faculty of Health, Research Center for Environmental Pollutants (Dr Mahdinia, Dr Heidari, Dr Soltanzadeh); Department of Internal Medicine, School of Medicine (Dr Adeli); Department of Epidemiology & Biostatistics, Faculty of Health, Neuroscience Research Center (Dr Mohammadbeigi), Qom University of Medical Sciences, Qom; and Department of Occupational Safety & Health Engineering, School of Public Health, Arak University of Medical Sciences, Arak (Dr Ghamari), Iran.
出版信息
J Occup Environ Med. 2020 Aug;62(8):e431-e435. doi: 10.1097/JOM.0000000000001932.
OBJECTIVE
This study aimed to investigate respiratory disorders associated with exposure to low concentrations of ammonia.
METHOD
This cohort study was conducted on 122 industrial workers. Data gathering were based on the officially registered data, the NMAM 6016 and the American Thoracic Society and European Respiratory Society protocols.
RESULTS
The prevalence rate of respiratory disorders significantly increased in the exposure group over 5 years (P < 0.05). The frequencies of these symptoms in the exposure group were significantly higher than non-exposure group (P < 0.05). Respiratory functions were decrease significantly in the exposure group and were lower than non-exposure group (P < 0.05). Exposure and the amount of exposure to ammonia had a significant relationship with respiratory disorders and respiratory functions (P < 0.05).
CONCLUSION
Exposure to ammonia lower than threshold limit value (TLV), can act as a risk factor of respiratory disorders.
目的
本研究旨在探讨接触低浓度氨与呼吸障碍的关系。
方法
本队列研究纳入了 122 名工业工人。数据收集基于 NMAM 6016 和美国胸科学会/欧洲呼吸学会的官方登记数据和协议。
结果
暴露组在 5 年内呼吸障碍的患病率显著增加（P<0.05）。暴露组的这些症状频率明显高于非暴露组（P<0.05）。暴露组的呼吸功能明显下降，且低于非暴露组（P<0.05）。暴露和接触氨的程度与呼吸障碍和呼吸功能显著相关（P<0.05）。
结论
接触低于阈限值（TLV）的氨可作为呼吸障碍的危险因素。
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