瑞典斯德哥尔摩4月下旬的4个新冠病毒基因组序列显示，刺突蛋白出现罕见突变。
Four SARS-CoV-2 Genome Sequences from Late April in Stockholm, Sweden, Reveal a Rare Mutation in the Spike Protein.
作者信息
Soratto Tatiany Aparecida Teixeira, Darban Hamid, Bjerkner Annelie, Coorens Maarten, Albert Jan, Allander Tobias, Andersson Björn
机构信息
Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
Department of Microbiology, Immunology, and Parasitology, Federal University of Santa Catarina, Florianopólis, Santa Catarina, Brazil.
出版信息
Microbiol Resour Announc. 2020 Aug 27;9(35):e00934-20. doi: 10.1128/MRA.00934-20.
Here, we report four coding-complete severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome sequences from Stockholm, Sweden, sampled in late April 2020. A rare variant at bp 23463 of the SARS-CoV-2 genome was found, which corresponds to the S1 subunit of the spike protein, changing an arginine (R) residue to histidine (H).
在此，我们报告了2020年4月下旬从瑞典斯德哥尔摩采集的4个编码完整的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）基因组序列。在SARS-CoV-2基因组的23463碱基对处发现了一个罕见变异，该位置对应于刺突蛋白的S1亚基，一个精氨酸（R）残基变为组氨酸（H）。
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