揭开弓形虫治疗的奥秘：从传统药物到纳米医学。
Unravelling Toxoplasma treatment: conventional drugs toward nanomedicine.
机构信息
Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
World J Microbiol Biotechnol. 2021 Feb 10;37(3):48. doi: 10.1007/s11274-021-03000-x.
Toxoplasma gondii is a worldwide protozoan parasite that infects almost all warm-blooded animals. Although human toxoplasmosis is mostly latent, pregnant women and immunocompromised patients need effective treatment. There are drugs of choice for treatment of toxoplasmosis; however, due to their side effects and/or their disease stage-specificity, prescription of them is limited. During recent years, nanomedicine has been employed to overcome limitations of conventional drugs. Here, we provided a state-of-the-art review of experimental toxoplasmosis treatment using nanotechnology.
刚地弓形虫是一种世界性的原生动物寄生虫，几乎感染所有温血动物。尽管人类弓形虫病大多呈潜伏性，但孕妇和免疫功能低下的患者需要有效的治疗。有一些药物是治疗弓形虫病的首选药物；然而，由于它们的副作用和/或疾病阶段特异性，它们的使用受到限制。近年来，纳米医学已被用于克服传统药物的局限性。在这里，我们提供了使用纳米技术治疗实验性弓形虫病的最新综述。
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