Plastic and Reconstructive Surgery, Surgical Science Department, University of Rome "Tor Vergata", Rome, Italy.
Scientific Director of AIRMESS, Academy of International Regenerative Medicine & Surgery Societies, Geneva, Switzerland.
Expert Opin Biol Ther. 2021 Nov;21(11):1443-1449. doi: 10.1080/14712598.2021.1908995. Epub 2021 Apr 5.
Many investigations showed that platelet-rich plasma (PRP), human follicles stem cells (HFSCs), and adipose-derived stem cells (ASCs), considered autologous stem cell-based therapy (ASC-BT), are effective for hair regrowth (HR) in patients affected by androgenetic alopecia and for wound healing (WH). The aim of this article is to analyze the and impact of different PRP, HFSCs, and ASCs preparation methods on HR and in WH.
The analyzed data intended to clarify the molecular mechanism in which PRP, HFSCs, and ASCs are involved, the clinical use and related indications, fully respecting the European rules. Comparative studies between different systems of PRP, HFSCs, and ASCs preparation revealed differences in terms of HR and WH.
Despite a lack of standardized protocols, there is convincing evidence with objective measurement modalities that display positive outcomes of ASC-BT in HR and WH.
许多研究表明,富血小板血浆(PRP)、人毛囊干细胞(HFSCs)和脂肪来源干细胞(ASCs)被认为是自体干细胞为基础的治疗(ASC-BT),可有效促进雄激素性脱发患者的头发生长(HR)和促进伤口愈合(WH)。本文旨在分析不同 PRP、HFSCs 和 ASC 制备方法对 HR 和 WH 的影响。
分析的数据旨在阐明 PRP、HFSCs 和 ASCs 参与的分子机制、临床应用及相关适应证,同时充分尊重欧洲规则。不同 PRP、HFSCs 和 ASC 制备系统之间的比较研究表明,在 HR 和 WH 方面存在差异。
尽管缺乏标准化方案,但客观测量方式显示出 ASC-BT 在 HR 和 WH 方面具有令人信服的积极效果。