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招募和留住感染艾滋病毒的女性参与临床研究:综述。

Recruitment and Retention of Women Living With HIV for Clinical Research: A Review.

机构信息

Johns Hopkins University School of Nursing, 525 N Wolfe St, Baltimore, MD, 21205, USA.

Department of Professional Practice, Inova Health System, Falls Church, VA, USA.

出版信息

AIDS Behav. 2021 Oct;25(10):3267-3278. doi: 10.1007/s10461-021-03273-1. Epub 2021 May 14.

Abstract

Women are underrepresented in HIV clinical research. However, there has not been a review on how to effectively recruit and retain women living with HIV in research. The purpose of this review is to describe recruitment and retention methods and factors associated with research participation among women living with HIV in the U.S. We searched PubMed, CINAHL, and Google and synthesized studies using thematic analysis. The most common method of recruiting women with HIV into research was through community-based HIV clinics, and the greatest yield was from word of mouth and a university HIV research center. Attrition may occur early and can be addressed by focusing on retention as early as study planning. Barriers to research participation for women can be addressed through retention methods discussed. We conclude that building relationships with community members and women living with HIV, being flexible, and implementing many methods is important for recruitment and retention.

摘要

女性在 HIV 临床研究中代表性不足。然而,目前还没有关于如何有效地招募和留住参与 HIV 研究的女性的综述。本综述的目的是描述美国 HIV 感染者参与研究的招募和保留方法以及与研究参与相关的因素。我们检索了 PubMed、CINAHL 和 Google,并使用主题分析对研究进行了综合。最常见的招募 HIV 女性参与研究的方法是通过社区 HIV 诊所,而最大的收获来自于口碑和大学 HIV 研究中心。流失可能发生得很早,可以通过在研究计划阶段就关注保留来解决。女性参与研究的障碍可以通过讨论的保留方法来解决。我们的结论是,与社区成员和 HIV 感染者建立关系、灵活应变以及采用多种方法对于招募和保留非常重要。

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