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《印度克什米尔 16 家医院医护人员中 SARS-CoV-2 的负担:一项血清流行病学研究》

The burden of SARS-CoV-2 among healthcare workers across 16 hospitals of Kashmir, India-A seroepidemiological study.

机构信息

Department of Community Medicine, Government Medical College, Srinagar, Jammu and Kashmir, India.

Department of Biochemistry, Government Medical College, Srinagar, Jammu and Kashmir, India.

出版信息

PLoS One. 2021 Nov 19;16(11):e0259893. doi: 10.1371/journal.pone.0259893. eCollection 2021.

Abstract

UNLABELLED

SARS-CoV-2 pandemic has greatly affected healthcare workers because of the high risk of getting infected. The present cross-sectional study measured SARS-CoV-2 antibody in healthcare workers of Kashmir, India.

METHODS

Serological testing to detect antibodies against nucleocapsid protein of SARS-CoV-2 was performed in 2003 healthcare workers who voluntarily participated in the study.

RESULTS

We report relatively high seropositivity of 26.8% (95% CI 24.8-28.8) for SARS-CoV-2in healthcare workers, nine months after the first case was detected in Kashmir. Most of the healthcare workers (71.7%) attributed infection to the workplace environment. Among healthcare workers who neither reported any prior symptom nor were they ever tested for infection by nasopharyngeal swab test, 25.5% were seropositive.

CONCLUSION

We advocate interval testing by nasopharyngeal swab test of all healthcare workers regardless of symptoms to limit the transmission of infection within healthcare settings.

摘要

目的

本横断面研究旨在检测印度克什米尔地区医护人员体内的 SARS-CoV-2 抗体。

方法

对 2003 名自愿参加研究的医护人员进行了针对 SARS-CoV-2 核衣壳蛋白的血清学检测。

结果

我们报告了相对较高的 SARS-CoV-2 血清阳性率为 26.8%(95%CI 24.8-28.8),这是在克什米尔地区首次发现病例九个月后得出的结果。大多数医护人员(71.7%)认为感染是由于工作场所环境所致。在没有任何症状且从未通过鼻咽拭子检测感染的医护人员中,有 25.5%的人血清呈阳性。

结论

我们主张对所有医护人员进行鼻咽拭子检测,无论症状如何,以限制感染在医疗机构内的传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f65/8604293/a1042ce4daa0/pone.0259893.g001.jpg

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