Department of Pediatrics and Child Health, Hawassa University, Hawassa, Ethiopia.
School of Nursing, Hawassa University, Hawassa, Ethiopia.
BMC Endocr Disord. 2022 Jun 15;22(1):161. doi: 10.1186/s12902-022-01070-y.
Glycemic control is an important part of diabetes management. Strict glycemic control has been shown to reduce the long-term complications of diabetes. However, achieving good glycemic control is challenging for people with diabetes especially in resource limited settings. The aim of this study was to assess glycemic control and identify its determinants among children and adolescents with diabetes.
A cross-sectional study among 116 children and adolescents with diabetes was done at a pediatric endocrine clinic in southern Ethiopia. Data on socioeconomic, demographic, nutrition, and diabetes related variables were collected. Glycemic control was assessed based on glycosylated hemoglobin level. Logistic regression analysis was used to identify predictors of glycemic control.
The mean glycated hemoglobin (HbA1c) of the participants was 9.6 ± 2.4% (81 ± 3 mmol/mol). Ninety seven (83.6%) of the study participants had poor glycemic control [HbA1c ≥7.5% (58 mmol/mol)]. The presence of lipodystrophic change at injection sites (p =0.028) and being from a family that cannot afford for insulin when there is no free supply (p =0.009) were associated with poor glycemic control.
The majority of children and adolescents with diabetes had poor glycemic control. Stakeholders shall focus on identifying strategies to improve the magnitude of poor glycemic control. More research is warranted to exhaustively list out factors contributing to poor glycemic control.
血糖控制是糖尿病管理的重要组成部分。严格的血糖控制已被证明可以减少糖尿病的长期并发症。然而,对于糖尿病患者,尤其是在资源有限的环境中,实现良好的血糖控制具有挑战性。本研究旨在评估儿童和青少年糖尿病患者的血糖控制情况,并确定其决定因素。
在埃塞俄比亚南部的一家儿科内分泌诊所进行了一项横断面研究,共纳入 116 名儿童和青少年糖尿病患者。收集了社会经济、人口统计学、营养和糖尿病相关变量的数据。血糖控制根据糖化血红蛋白水平进行评估。采用逻辑回归分析确定血糖控制的预测因素。
参与者的平均糖化血红蛋白(HbA1c)为 9.6±2.4%(81±3mmol/mol)。97 名(83.6%)研究参与者血糖控制不佳[HbA1c≥7.5%(58mmol/mol)]。注射部位存在脂肪营养不良改变(p=0.028)和家庭在没有免费供应时无法负担胰岛素(p=0.009)与血糖控制不佳相关。
大多数儿童和青少年糖尿病患者血糖控制不佳。利益相关者应关注确定改善血糖控制不佳程度的策略。需要进行更多的研究,以详尽列出导致血糖控制不佳的因素。