一种用于检测铜和锌的高效四氢喹唑啉-2-胺衍生物接枝纤维素荧光探针。

An efficient tetrahydroquinazolin-2-amine derivative-grafted cellulose fluorescent probe for detection of Cu and Zn.

作者信息

Meng Zhiyuan, Zhao Fei, Wang Zhonglong, Yang Yiqin, Wang Shifa

机构信息

Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, International Innovation Center for Forest Chemicals and Materials, College of Chemical Engineering, College of Light Industry and Food, Nanjing Forestry University, Nanjing 210037, China.

出版信息

Carbohydr Polym. 2023 Mar 1;303:120445. doi: 10.1016/j.carbpol.2022.120445. Epub 2022 Dec 12.

DOI:10.1016/j.carbpol.2022.120445

PMID:36657857

Abstract

Cu and Zn play crucial roles in many physiological processes, and their disorder will cause harm to human health. An efficient difunctional fluorescent probe CMC-GE-PQA for simultaneous detection of Cu and Zn was synthesized based on carboxymethyl cellulose. The probe CMC-GE-PQA exhibited a moderate blue fluorescence color. Interestingly, this probe showed a distinct fluorescence enhancement response toward Zn, while it displayed a significant fluorescence quenching response toward Cu. The detection limits of CMC-GE-PQA for Cu and Zn were calculated as low as 5.0 × 10 M and 1.0 × 10 M, respectively. The detection mechanisms of CMC-GE-PQA for Cu and Zn were fully verified by Job's plot, X-ray photoelectron spectroscopy analysis. The probe CMC-GE-PQA was applied to determine the trace amounts of Cu and Zn in environmental water samples. In addition, the probe CMC-GE-PQA-based fluorescent film and hydrogel were manufactured to achieve the portable detection of Cu and Zn.

摘要

铜和锌在许多生理过程中发挥着关键作用，它们的紊乱会对人体健康造成危害。基于羧甲基纤维素合成了一种用于同时检测铜和锌的高效双功能荧光探针CMC-GE-PQA。探针CMC-GE-PQA呈现出适度的蓝色荧光。有趣的是，该探针对锌表现出明显的荧光增强响应，而对铜则表现出显著的荧光猝灭响应。计算得出CMC-GE-PQA对铜和锌的检测限分别低至5.0×10⁻⁸ M和1.0×10⁻⁷ M。通过Job曲线、X射线光电子能谱分析充分验证了CMC-GE-PQA对铜和锌的检测机制。探针CMC-GE-PQA用于测定环境水样中的痕量铜和锌。此外，制备了基于探针CMC-GE-PQA的荧光膜和水凝胶以实现对铜和锌的便携式检测。