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一种用于理解疫苗接种和治疗对传染病传播动力学影响的循环行为建模方面。

A cyclic behavioral modeling aspect to understand the effects of vaccination and treatment on epidemic transmission dynamics.

机构信息

Department of Mathematics, Bangladesh University of Engineering and Technology, Dhaka, 1000, Bangladesh.

Department of Mathematics, Feni University, Feni, Bangladesh.

出版信息

Sci Rep. 2023 May 23;13(1):8356. doi: 10.1038/s41598-023-35188-3.

Abstract

Evolutionary epidemiological models have played an active part in analyzing various contagious diseases and intervention policies in the biological sciences. The design in this effort is the addition of compartments for treatment and vaccination, so the system is designated as susceptible, vaccinated, infected, treated, and recovered (SVITR) epidemic dynamic. The contact of a susceptible individual with a vaccinated or an infected individual makes the individual either immunized or infected. Inventively, the assumption that infected individuals enter the treatment and recover state at different rates after a time interval is also deliberated through the presence of behavioral aspects. The rate of change from susceptible to vaccinated and infected to treatment is studied in a comprehensive evolutionary game theory with a cyclic epidemic model. We theoretically investigate the cyclic SVITR epidemic model framework for disease-free and endemic equilibrium to show stable conditions. Then, the embedded vaccination and treatment strategies are present using extensive evolutionary game theory aspects among the individuals in society through a ridiculous phase diagram. Extensive numerical simulation suggests that effective vaccination and treatment may implicitly reduce the community risk of infection when reliable and cheap. The results exhibited the dilemma and benefitted situation, in which the interplay between vaccination and treatment evolution and coexistence are investigated by the indicators of social efficiency deficit and socially benefited individuals.

摘要

进化流行病学模型在分析生物科学中的各种传染病和干预政策方面发挥了积极作用。这项工作的设计是增加了治疗和疫苗接种的隔室,因此该系统被指定为易感、接种、感染、治疗和恢复(SVITR)的流行动力学。易感个体与接种或感染个体的接触会使个体免疫或感染。创造性地,还通过存在行为方面来考虑感染个体在经过一段时间间隔后以不同的速率进入治疗和恢复状态的假设。通过循环流行模型的综合进化博弈论研究了从易感到接种和感染到治疗的变化率。我们从理论上研究了无病和地方病平衡点的循环 SVITR 流行模型框架,以显示稳定条件。然后,通过荒谬的相图,通过社会中个体的广泛进化博弈论方面呈现了嵌入式疫苗接种和治疗策略。广泛的数值模拟表明,当可靠且廉价时,有效的疫苗接种和治疗可能会含蓄地降低社区感染的风险。结果展示了困境和受益情况,通过社会效率赤字和受益个体的指标研究了疫苗接种和治疗进化以及共存之间的相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09e2/10206095/3a3e9c42534a/41598_2023_35188_Fig1_HTML.jpg

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